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IN THIS ISSUE OF JAMA
Audio Highlights
Editor's Summary Audio: Oxygen Targets in the ICU, Acetaminophen During Pregnancy and Risk of Neurodevelopmental Disorders, Alcohol Use Disorder Screening Tools, and more
ORIGINAL INVESTIGATION
Caring for the Critically Ill Patient
Lower vs Higher Oxygenation Target and Days Alive Without Life Support in COVID-19: The HOT-COVID Randomized Clinical Trial
Frederik M. Nielsen, MD; Thomas L. Klitgaard, MD, PhD; Martin Siegemund, MD; et al.
Editorial: Oxygen Supplementation in COVID-19—How Much Is Enough?; Richard M. Schwartzstein, MD
Caring for the Critically Ill Patient
Individualized Treatment Effects of Oxygen Targets in Mechanically Ventilated Critically Ill Adults
Kevin G. Buell, MBBS; Alexandra B. Spicer, MS; Jonathan D. Casey, MD, MSc; et al.
Editorial: Your Mileage May Vary: Toward Personalized Oxygen Supplementation; Derek C. Angus, MD, MPH
Acetaminophen Use During Pregnancy and Children’s Risk of Autism, ADHD, and Intellectual Disability
Viktor H. Ahlqvist, PhD; Hugo Sjöqvist, MSc; Christina Dalman, MD, PhD; et al.
Earn CME credit
RESEARCH LETTER
Mortality Among Users of Anabolic Steroids
Josefine Windfeld-Mathiasen, MD; Ida M. Heerfordt, MD, PhD; Kim Peder Dalhoff, MD, DMSc; et al.
State Coverage and Reimbursement of Antiobesity Medications in Medicaid
Benjamin Y. Liu, MD; Benjamin N. Rome, MD, MPH
VIEWPOINT
The Limits of Clinician Vigilance as an AI Safety Bulwark
Julia Adler-Milstein, PhD; Donald A. Redelmeier, MD; Robert M. Wachter, MD
A PIECE OF MY MIND
The Tree of Knowledge
Harry Doernberg, MM
EDITORIAL
Oxygen Supplementation in COVID-19—How Much Is Enough?
Richard M. Schwartzstein, MD
Your Mileage May Vary: Toward Personalized Oxygen Supplementation
Derek C. Angus, MD, MPH
2023 Year in Review and What’s Ahead at JAMA
Kirsten Bibbins-Domingo, PhD, MD, MAS; Annette Flanagin, RN, MA; Stacy Christiansen, MA; et al.
THE RATIONAL CLINICAL EXAMINATION
Does This Patient Have Alcohol Use Disorder? The Rational Clinical Examination Systematic Review
Evan Wood, MD, PhD; Jeffrey Pan, PharmD; Zishan Cui, PhD; et al.
Earn CME credit
JAMA GUIDE TO STATISTICS AND METHODS
Using Effect Scores to Characterize Heterogeneity of Treatment Effects
Guanbo Wang, PhD; Patrick J. Heagerty, PhD; Issa J. Dahabreh, MD, ScD
JAMA INSIGHTS
Diagnosis and Management of Myotonic Dystrophy Type 1
Julia Hartman, BS; Tejal Patki, BS; Nicholas E. Johnson, MD, Msci
Earn CME credit
EDITOR'S NOTE
Trading Places, Becoming One
Rafael Campo, MD, MA
MEDICAL NEWS & PERSPECTIVES
All of Us Program Illustrates What Less-Diverse Genomics Studies Might Be Missing
Rita Rubin, MA
Quick Uptakes
NIH Study Provides Long-Awaited Insight Into Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Quinn Eastman, PhD
Medical News Audio: March 2024 Medical News Summary
MEDICAL NEWS IN BRIEF
One in 8 People Worldwide Are Obese
Samantha Anderer
Cannabis Use Linked to Elevated Myocardial Infarction and Stroke Risk
Samantha Anderer
Meta-Analysis: Females at Higher Risk of Death From Staph Infection
Samantha Anderer
Brain Waves Appear to Wash Out Waste During Sleep
Samantha Anderer
POETRY AND MEDICINE
Hey Doc
John Petrilli, MD
Editor's Note: Trading Places, Becoming One; Rafael Campo, MD, MA
JAMA REVISITED
The Private Physician and Preventive Medicine: Bruce H. Douglas, M.D., Detroit
PEER REVIEWERS LIST
JAMA Peer Reviewers in 2023
Editorial: 2023 Year in Review and What’s Ahead at JAMA; Kirsten Bibbins-Domingo, PhD, MD, MAS; Annette Flanagin, RN, MA; Stacy Christiansen, MA; Hannah Park; Greg Curfman, MD
JAMA PATIENT PAGE
What Is Perinatal Depression?
Rebecca Voelker, MSJ
AUDIO
Editor's Summary Audio
Oxygen Targets in the ICU, Acetaminophen During Pregnancy and Risk of Neurodevelopmental Disorders, Alcohol Use Disorder Screening Tools, and more
Medical News Audio
March 2024 Medical News Summary
COMMENT & RESPONSE
ECMO and Prone Position in Patients With Severe ARDS
Charles Wiener, MD; Richard K. Albert, MD
ECMO and Prone Position in Patients With Severe ARDS
G. Jan Zijlstra, MD, PhD; Harm-Jan de Grooth, MD, PhD
ECMO and Prone Position in Patients With Severe ARDS—Reply
Matthieu Schmidt, MD, PhD; David Hajage, MD, PhD; Alain Combes, MD, PhD
Breast Cancer and Pregnancy in Young BRCA Carriers
Steven A. Narod, MD
Breast Cancer and Pregnancy in Young BRCA Carriers—Reply
Eva Blondeaux, MD; Ann H. Partridge, MD; Matteo Lambertini, MD
Affiliation Bias in Peer Review of Abstracts
Robert J. Gallo, MD; Thomas Savage, MD; Jonathan H. Chen, MD, PhD
AI in Medicine
Affiliation Bias in Peer Review of Abstracts—Reply
Dario von Wedel; Denys Shay, MD; Maximilian S. Schaefer, MD, PhD
CORRECTION
Data Errors
Article Retraction
JAMA MASTHEAD
JAMA
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