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SHARE YOUR OPINION: TAKE THE JAMA+ TRIALS POLL
What do you think about pragmatic clinical trials? Answer this month’s poll question and we’ll share back what the JAMA+ Trials community thinks next month.
Take the poll
EDITOR’S CHOICE: CLINICAL TRIAL OF THE YEAR
Protection Against Persistent HPV-16/18 Infection After Different Number of Doses of Quadrivalent Vaccine in Girls and Young Women: A Randomized Clinical Trial
Chantal Sauvageau, MD, MSc; Marie-Hélène Mayrand, MD, PhD; Manale Ouakki, MSc; et al
Find out why JAMA Network Open Editor in Chief Dr Perencevich chose this "cost-effective and efficient" randomized trial that exemplifies how evidence-based public health decision should be made.
Read the Editor's Note
RESEARCH, REVIEWS, AND COMMENTARY
Original Investigation | JAMA Network Open
Regional Variation in Bladder Cancer Clinical Trial Availability in the US
Koral U. Shah, MD; Salvador Jaime-Casas, MD; Ruchi Agarwal et al.
Research Letter | JAMA Network Open
Large Language Models and Adverse Event Detection Within Immunotherapy Clinical Trials
Marianna V. Elia, MSE; Isabel D. Friesner, BA; Daniel Kwon, MD; et al.
Viewpoint | JAMA Health Forum
Opportunities and Risks of a Single-Trial Default for FDA Drug Approval
Reshma Ramachandran, MD, MPP, MHS; Rachel E. Sachs, JD, MPH; Patricia J. Zettler, JD; et al.
Viewpoint | JAMA Psychiatry
The Case for More Aggressive Masking in Psychedelic Trials
Kevin H. Yang, MD; Boris D. Heifets, MD, PhD; Andrew Krystal, MD, PhD; et al.
MULTIMEDIA
From ESC: Statin Nonadherence, LDL Cholesterol Lowering After Acute MI, Ablation Therapy for Atrial Fibrillation, Advances in Cardiac Amyloidosis, and more
In this podcast, hear about several randomized clinical trials published in JAMA and JAMA Cardiology that were presented at this year’s European Society of Cardiology Congress, including the Amundsen RCT, the ADHERE-ASCVD, and the CMR GUIDE RCT.
INTEGRATING CLINICAL TRIALS AND PRACTICE
Viewpoint | JAMA
Untapped Potential? Representativeness in Pragmatic Clinical Trials
Caleigh Propes, BA; Kayla Mehl, PhD; Stephanie R. Morain, PhD, MPH
Search & Browse Clinical Trials
Explore recent trials published across the JAMA Network using keywords and curated filters.
Search & Browse
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