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JAMA Internal Medicine New Issue August 2025; Volume 185, Number 8

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New Issue

August 2025; Volume 185, Number 8
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Viewpoint

Less Is More

The Impact of Definitions of Disease on Overdiagnosis

Kari A. O. Tikkinen, MD, PhD; Alex L. E. Halme, BSc; Gordon H. Guyatt, MD; et al.

Women's Health

Abortion Shield Laws in Action

David S. Cohen, JD; Greer Donley, JD; Rachel Rebouché, JD

Long-Term Health Implications of the Los Angeles Wildfires and Insights From Military Burn Pit Exposures

Eric Goralnick, MD, MS; Kari Nadeau, MD, PhD; Rachel Moyal-Smith, DrPH, PA-C; et al.

Inside Story

Chimneys

David B. Reuben, MD

The Persons Behind Our Patients—Individualized Assessment Tools for Personalized Care

Ruchi Bhatia, MD

Reading Room

Eleanor R. Menzin, MD

I’m Stepping Away. Can You Cover for Me?—Supporting Faith-Based Practices

Fawad A. Khan, MD, CPPS

The Power of Faith

Xianshi Zhou, MD

Original Investigation

Less Is More

Diabetes Deprescribing in Older Adults: A Randomized Clinical Trial

Richard W. Grant, MD, MPH; Ilana Peterson, MPH; Jodi M. McCloskey, MPH; et al.

Dietary Patterns, Sodium Reduction, and Blood Pressure in Type 2 Diabetes: The DASH4D Randomized Clinical Trial

Scott J. Pilla, MD, MHS; Hsin-Chieh Yeh, PhD; Christine M. Mitchell, ScM; et al.

Transfusion Strategy Effect on Quality of Life in Patients With Myocardial Infarction and Anemia: A Secondary Analysis of the MINT Randomized Clinical Trial

Micah T. Prochaska, MD, MSc; Gerard T. Portela, PhD; Maria Mori Brooks, PhD; et al.

Effectiveness of Text-Only E-Cigarette Warnings: A Meta-Analysis

Youjin Jang, PhD; Jessica Shaw, MA; Olivia A. Wackowski, PhD; et al.

Aging and Health

Early Invasive or Conservative Strategies for Older Patients With Acute Coronary Syndromes: A Meta-Analysis

Rohin K. Reddy, MBBS; David Koeckerling, MD; Christian Eichhorn, MD; et al.

Patient Navigation Services for Breast and Cervical Cancer Screening and Follow-Up: A Meta-Analysis

Heidi D. Nelson, MD, MPH; Amy G. Cantor, MD, MPH; Miranda Pappas, MA; et al.

Adverse Liver Outcomes, Cardiovascular Events, and Mortality in Steatotic Liver Disease

Pedro Ochoa-Allemant, MD; Rebecca A. Hubbard, PhD; David E. Kaplan, MD, MSc; et al.

Health Care Policy and Law

FDA Authorization of Therapeutic Devices Under the Breakthrough Devices Program

Kushal T. Kadakia, MD; Sanket S. Dhruva, MD, MHS; Joseph S. Ross, MD, MHS; et al.

Climate Change and Health

Budesonide-Formoterol Metered-Dose Inhaler vs Fluticasone-Salmeterol Dry-Powder Inhaler

Alexander S. Rabin, MD; Sarah M. Seelye, PhD; Julien B. Weinstein, MS; et al.

Diseases Common in Persons With Cystic Fibrosis Among CFTR Heterozygotes

Chenjie Zeng, PhD, MPH; Sangwoo T. Han, PhD; Thomas A. Cassini, MD; et al.

Editorial

Updated USPSTF Guidelines on Screening for Intimate Partner Violence and Caregiver Abuse

Eve Rittenberg, MD, MA; Kenneth E. Covinsky, MD, MPH; Deborah Grady, MD, MPH

Editorial: The Evidence for Intimate Partner Violence and Elder Abuse Screening: Stagnation at a Critical Juncture; Melissa A. Simon, MD, MBA, MPH

Invited Commentary

Scratching the Surface of Deprescribing in Diabetes

Scott J. Pilla, MD, MHS; Nancy L. Schoenborn, MD, MHS

The Future of e-Cigarette Health Warnings

Ebbie Kalan, PhD; Olatokunbo Osibogun, PhD; Ziyad Ben Taleb, MD, PhD

Aging and Health

Addressing the Hospital Boarding Crisis in the US—Time to Act

Maura Kennedy, MD, MPH; Tony Rosen, MD, MPH; Kevin Biese, MD, MAT

Podcast: National Trends in Prolonged Emergency Department Length of Stay Among Older Adults: 2017-2024

Health Equity

Physicians in Training, Communities in Need—Reimagining GME Policy for the Indian Health Service

Eve J. Higginbotham, SM, MD, ML; Roy Wade Jr, MD, PhD, MPH, MSHP

Editor's Note

The Converging Crises of Extreme Heat and Homelessness

Nathan M. Stall, MD, PhD; Giselle Corbie, MD, MSc; Sharon K. Inouye, MD, MPH; et al.

Teachable Moment

Less Is More

Continuous Glucose Monitor Use—Avoiding Overuse

Kailynn M. Barton, BS; Jeanne H. Steppel-Reznik, MD; Clement D. Lee, MD, MSc

Earn CME credit

Research Letter

Climate Change and Health

Heat-Related Illness Among US Patients Experiencing Homelessness

Taylor Nicole Weckstein, BS; Steffie Woolhandler, MD, MPH; David U. Himmelstein, MD; et al.

Editor's Note: The Converging Crises of Extreme Heat and Homelessness; Nathan M. Stall, MD, PhD; Giselle Corbie, MD, MSc; Sharon K. Inouye, MD, MPH; Cary P. Gross, MD

Aging and Health

Prolonged Emergency Department Stays for Older US Adults

Adrian D. Haimovich, MD, PhD; Sarah D. Berry, MD, MPH; Bruce E. Landon, MD, MBA

Comparing Indian Health Service Sites to Rural Physician Teaching Hospitals

Matthew Tobey, MD; Mukesh Adhikari, MPH; George M. Holmes, PhD; et al.

Continuous Medical Knowledge Assessment Progress Report Score and Hospitalized Patient Outcomes

Bradley M. Gray, PhD; Jonathan L. Vandergrift, MS; Rebecca S. Lipner, PhD; et al.

Clinical Insights

Women's Health

Gender-Affirming Feminizing Hormone Therapy

Zil Goldstein, FNP; Matthew D. Krasowski, MD, PhD; Dina N. Greene, PhD

Earn CME credit

New Frontier, New Challenges—Recognizing and Managing Adverse Effects of Antiamyloid Therapies

Megan A. Rech, PharmD, MS; Neelum T. Aggarwal, MD; Ula Hwang, MD, MPH

Earn CME credit

Challenges in Clinical Electrocardiography

Atrioventricular Block With Abnormal P Wave

Jun-Peng Liu, PhD, MD; Jie-Fu Yang, PhD, MD; Tong Zou, PhD, MD

Earn CME credit

Audio

National Trends in Prolonged Emergency Department Length of Stay Among Older Adults: 2017-2024

Comment & Response

Correction Rate Matters in Severe Hyponatremia

Zhenjiao Liang, MD; Yingdi Yuan, MS; Xiaoping Wang, MD

Correction Rate Matters in Severe Hyponatremia

Saeed Rashaad Mohammed, BMedSci, MBBS; Surujpal Teelucksingh, MBBS, MBA, PhD

Correction Rate Matters in Severe Hyponatremia

Harish Seethapathy, MD; Aneesh B. Singhal, MD; Sagar U. Nigwekar, MD, MMSc

Enticing but Confounded Evidence for Fast Sodium Correction

Eric Raphael Gottlieb, MD, MS; Leo Anthony Celi, MD, MPH

Enticing but Confounded Evidence for Fast Sodium Correction—Reply

Juan Carlos Ayus, MD; Michael L. Moritz, MD; Agustín Ciapponi, MD, MSc, PhD

Correction Rate Matters in Severe Hyponatremia—Reply

Juan Carlos Ayus, MD; Michael L. Moritz, MD; Agustín Ciapponi, MD, MSc, PhD

Health Equity

Overall Effects and Masking of Important Differences in Risk Factors

Joanna M. Davies, PhD, MSc, BA; Claud Regnard, MBChB; Katherine E. Sleeman, BSc, MBBS, PhD

Editor's Note: Centering Patients and Evidence in Debates About Medical Assistance in Dying; Nathan M. Stall, MD, PhD; Cary P. Gross, MD

Health Care Policy and Law

Overall Effects and Masking of Important Differences in Risk Factors—Reply

James Downar, MD, MHSc; Bregje Onwuteaka-Philipsen, PhD; Thaddeus Pope, JD, PhD

Doxycycline Postexposure Prophylaxis Could Accelerate the Emergence of Gonococcal Ceftriaxone Resistance

Chris Kenyon, MD, MPH, PhD

Doxycycline Postexposure Prophylaxis Could Accelerate the Emergence of Gonococcal Ceftriaxone Resistance—Reply

Michael W. Traeger, PhD; Jonathan E. Volk, MD; Julia L. Marcus, PhD

Correction

Error in Funding Disclosure

Error in Conflict of Interest Disclosures

Error in P Value

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