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Viewpoint
Aging and Health
The Evolving Case for Skin Failure—Beyond Pressure Injury
Dan R. Berlowitz, MD, MPH; Jeffrey M. Levine, MD, AGSF
Editor's Note: Pressure Injuries and Skin Failure—Pressure Still Matters; Lona Mody, MD, MSc; Eve Rittenberg, MD; Sharon K. Inouye, MD, MPH
Climate Change and Health
Addressing the Health Impacts of Climate Change in Older Adults
Gabrielle M. Katz, BHSc; Danielle Arigoni, MRP; Mary B. Rice, MD, MPH; et al.
The Future of US Sexual and Gender Minority Health Policy
Sahil Sandhu, MSc; Michael Liu, MPhil; Alex S. Keuroghlian, MD, MPH
Health Care Policy and Law
The Medical, Ethical and Legal Case Against Dual Stabilization
Elizabeth Tobin-Tyler, JD; Benjamin Brown, MD
Inside Story
Physician Work Environment and Well-Being
Proposed Framework for Setting Practical and Ethical Boundaries in Medicine
Sarah C. Hull, MD, MBE; Nancy R. Angoff, MD, MPH, MEd
Feel Your Way Forward
Jiahui Su; Kaili Yang, MD; Shengwei Ren, MD, PhD
Original Investigation
Buprenorphine, Pain, and Opioid Use in Patients Taking High-Dose Long-Term Opioids: A Randomized Clinical Trial
William C. Becker, MD; Karen H. Seal, MD, MPH; David B. Nelson, PhD; et al.
Editorial: Integrating Buprenorphine Into Chronic Pain Treatment—Putting the Choice in VOICE; Michael A. Incze, MD, MSEd; Timothy S. Anderson, MD, MAS
Growing Health Concern Regarding Gambling Addiction in the Age of Sportsbooks
Atharva Yeola, BS; Matthew R. Allen, BS; Nimit Desai, BS; et al.
Podcast: Gambling Addiction in the Age of Sportsbooks
Termination of Resuscitation Rules for In-Hospital Cardiac Arrest
Mathias J. Holmberg, MD, PhD, MPH; Asger Granfeldt, MD, PhD, DMSc; Ari Moskowitz, MD, MPH; et al.
Editor's Note: Decision Rules for Termination of Resuscitation—A Roadmap for Challenging Terrain; Ilana B. Richman, MD, MHS; Sharon K. Inouye, MD, MPH; Tracy Wang, MD, MHS, MSc
Glucose-Lowering Medications and Risk of Chronic Obstructive Pulmonary Disease Exacerbations in Patients With Type 2 Diabetes
Avik Ray, MD, MS; Julie M. Paik, MD, ScD, MPH; Deborah J. Wexler, MD, MSc; et al.
Editor's Note: Pleotropic Effects of Glucose-Lowering Medications—Need for Cautious Interpretation of Target Trial Emulation Studies; Nathan M. Stall, MD, PhD; Timothy S. Anderson, MD, MAS; Kenneth E. Covinsky, MD, MPH
Climate Change and Health
Extreme Heat and Hospitalization Among Older Persons With Alzheimer Disease and Related Dementias
Scott W. Delaney, ScD, JD, MPH; Angela Stegmuller, MS; Daniel Mork, PhD; et al.
Medicare Opioid Policy and Opioid Use in Beneficiaries With Disabilities
Hefei Wen, PhD; Alyssa Halbisen, MPH; Ann M. Thomas, PhD; et al.
Comparative Bleeding Risk in Older Patients With HIV and Atrial Fibrillation Receiving Oral Anticoagulants
Claire M. Quinlan, MD; Jerry Avorn, MD; Aaron S. Kesselheim, MD, JD, MPH; et al.
Less Is More
Telemedicine Adoption and Low-Value Care Use and Spending Among Fee-for-Service Medicare Beneficiaries
Ishani Ganguli, MD, MPH; Christopher Lim, BA; Nicholas Daley, AB; et al.
Podcast: Telemedicine Adoption and Low-Value Care Use and Spending Among Fee-for-Service Medicare Beneficiaries
Invited Commentary
Gambling Harms in the Era of Legal Gambling Expansion—A Growing Health Problem
Daria Ukhova, PhD; Rachel Volberg, PhD
Podcast: Gambling Addiction in the Age of Sportsbooks
Editor's Note
Pressure Injuries and Skin Failure—Pressure Still Matters
Lona Mody, MD, MSc; Eve Rittenberg, MD; Sharon K. Inouye, MD, MPH
Decision Rules for Termination of Resuscitation—A Roadmap for Challenging Terrain
Ilana B. Richman, MD, MHS; Sharon K. Inouye, MD, MPH; Tracy Wang, MD, MHS, MSc
Pleotropic Effects of Glucose-Lowering Medications—Need for Cautious Interpretation of Target Trial Emulation Studies
Nathan M. Stall, MD, PhD; Timothy S. Anderson, MD, MAS; Kenneth E. Covinsky, MD, MPH
Patient Portals—Balancing Workload and Opportunity
Ilana B. Richman, MD, MHS; Ishani Ganguli, MD, MPH; Eve Rittenberg, MD, MA
Review
Diagnosis and Management of Monoclonal Gammopathy of Undetermined Significance: A Review
Yuxin Liu, MD; Anna L. Parks, MD
Earn CME credit
Teachable Moment
Benzocaine-Induced Methemoglobinemia After Nasogastric Tube Insertion
Robert T. Williams, MD, PhD; Brett G. Fischer, MD
Earn CME credit
Research Letter
Physician Work Environment and Well-Being
Trends in Physician Electronic Health Record Time and Message Volume
A Jay Holmgren, PhD, MHI; Nate C. Apathy, PhD; Christine A. Sinsky, MD; et al.
Editor's Note: Patient Portals—Balancing Workload and Opportunity; Ilana B. Richman, MD, MHS; Ishani Ganguli, MD, MPH; Eve Rittenberg, MD, MA
Heterogeneity of Primary Outcomes in Large Atherosclerotic Cardiovascular Disease Trials Published in Prominent Medical Journals
Daniel Shepshelovich, MD; Dafna Yahav, MD; Danielle R. Rome, MD, MPH; et al.
Shareholder Payouts Among Large Publicly Traded Health Care Companies
Victor Roy, MD, PhD; Victor Amana, MPH; Joseph S. Ross, MD, MHS; et al.
Comparison of Clinical Evidence Submitted to the FDA and EMA for Cell and Gene Therapies
Magdi Elsallab, MD, PhD; Sandra Gillner, PhD; Florence T. Bourgeois, MD, MPH
Guide to Statistics and Methods
Emulating a Target Trial Using Observational Data
Basma N. Dib, MPH; Sonja A. Swanson, ScD
Earn CME credit
Audio
Gambling Addiction in the Age of Sportsbooks
Telemedicine Adoption and Low-Value Care Use and Spending Among Fee-for-Service Medicare Beneficiaries
Comment & Response
Complexity and Challenges of Measuring PrEP Adherence
David Garcia-Martinez, PharmD; Inés Soto-Baselga, PharmD, MSc; Noelia Garrido-Peño, PharmD, MSc
Complexity and Challenges of Measuring PrEP Adherence—Reply
Lorraine T. Dean, ScD
More on Antihypertensive Medications and Cognitive Function in Nursing Home Residents
Wang Mei, RN; Li Yue, RN; Wang Jiachun, RN
Aging and Health
More on Antihypertensive Medications and Cognitive Function in Nursing Home Residents
Ping-Hao Chiang, MD; Chieh-Hsuan Tsai, MD
More on Antihypertensive Medications and Cognitive Function in Nursing Home Residents—Reply
Bocheng Jing, MS; W. James Deardorff, MD; Michelle C. Odden, PhD
Possible Misdiagnosis of Asystole in Clinical Challenge
Laszlo Littmann, MD, PhD
Antihypertensive Medications in Patients With Weight Loss
Farrin A. Manian, MD, MPH
Antihypertensive Medications in Patients With Weight Loss—Reply
Kagan E. Karakus, MD; Viral N. Shah, MD; Halis K. Akturk, MD
Denominator and Composite Calculation Errors in Study of Health System Low-Value Services
Ishani Ganguli, MD, MPH
Importance of Arm Position and Cuff Width
Paolo Palatini, MD
Importance of Arm Position and Cuff Width
Merrill F. Elias, PhD, MPH; Craig J. Brown, MD
Importance of Arm Position and Cuff Width—Reply
Hairong Liu, MHS; Lawrence J. Appel, MD, MPH; Tammy M. Brady, MD, PhD
Errors From Incorrect Description of the Study Sample
Hyeun Ah Kang, PhD
Correction
Denominator and Composite Calculation Errors
Errors in Key Points, Abstract, Text, Figures, Table 2, and Supplement 1
JAMA Internal Medicine Masthead
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