JAMA + AI Weekly Update July 26, 2025

Melanoma cases are rising globally, and early detection is key to better outcomes. Can AI help?

In a new episode of JAMA+ AI Conversations, JAMA+ AI Editor-in-Chief Roy Perlis, MD, talks with Daniel Lindsay, PhD, about his research comparing the addition of 3D total-body photography and sequential digital dermoscopy imaging to telehealth visits with usual care — and the cost-effectiveness of doing so.

Read the Editor’s Note and listen to the conversation.

Editor’s Picks in this week’s JAMA+ AI:

• A new AI system can automatically interpret echocardiograms. In a JAMA Original Investigation, researchers showed their system maintained high accuracy across geography and time, even with more limited.
• Can an AI-driven system predict cutaneous squamous cell carcinoma? In an Original Investigation published in JAMA Dermatology, researchers found the AIRIS system, a LLM using retrieval augmented generation, outperformed current systems. In a related Editorial about the success of AIRIS, the authors call for a “strong collaboration between clinicians, statisticians, and AI practitioners” to ensure clinical applicability of AI advances.