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IN THIS ISSUE OF JAMA
Audio Highlights
Audio Editors' Summary: Theme Issue on Firearms and Violence, Featuring Viewpoints, Editorials, Medical News, and more
ORIGINAL INVESTIGATION
Effect of High-Flow Nasal Cannula Oxygen vs Standard Oxygen Therapy on Mortality in Patients With Respiratory Failure Due to COVID-19: The SOHO-COVID Randomized Clinical Trial
Jean-Pierre Frat, MD, PhD; Jean-Pierre Quenot, MD, PhD; Julio Badie, MD; et al.
Editorial: Respiratory Support in the Time of COVID-19; Alistair D. Nichol, PhD; Cecilia O’Kane, PhD; Daniel F. McAuley, MD
Effect of First-Line Serplulimab vs Placebo Added to Chemotherapy on Survival in Patients With Extensive-Stage Small Cell Lung Cancer: The ASTRUM-005 Randomized Clinical Trial
Ying Cheng, MD; Liang Han, MD; Lin Wu, PhD; et al.
Editorial: Serplulimab With Chemotherapy in Extensive-Stage SCLC; Noura J. Choudhury, MD; Gregory J. Riely, MD, PhD
Five-Year Outcomes in Patients With Fully Magnetically Levitated vs Axial-Flow Left Ventricular Assist Devices in the MOMENTUM 3 Randomized Trial
Mandeep R. Mehra, MD, MSc; Daniel J. Goldstein, MD; Joseph C. Cleveland, MD; et al.
Editorial: Left Ventricular Assist Devices in Advanced Heart Failure; Mark H. Drazner, MD, MSc
RESEARCH LETTER
SARS-CoV-2 Infections and Presymptomatic Type 1 Diabetes Autoimmunity in Children and Adolescents From Colorado, USA, and Bavaria, Germany
Marian Rewers, MD, PhD; Ezio Bonifacio, PhD; Dominik Ewald, MD; et al.
US PREVENTIVE SERVICES TASK FORCE
Recommendation Statement
Screening for Syphilis Infection in Nonpregnant Adolescents and Adults: US Preventive Services Task Force Reaffirmation Recommendation Statement
US Preventive Services Task Force
Earn CME credit
Editorial: The Critical Need to Modernize Syphilis Screening ; Susan Tuddenham, MD, MPH; Khalil G. Ghanem, MD, PhD
JAMA Dermatology Editorial: Resurgence of Syphilis in the US—USPSTF Reaffirms Screening Guidelines ; Erin H. Amerson, MD; Herbert B. Castillo Valladares, MD, MHS; Kieron S. Leslie, MD
JAMA Network Open Editorial: Screening for Syphilis in Nonpregnant Adults and Adolescents ; Ronnie M. Gravett, MD; Jeanne Marrazzo, MD, MPH
JAMA Patient Page: Screening for Syphilis; Jill Jin, MD, MPH
Audio Author Interview: USPSTF Recommendation: Syphilis Screening in Nonpregnant Adolescents and Adults
Evidence Report
Screening for Syphilis Infection in Nonpregnant Adults and Adolescents: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force
Michelle L. Henninger, PhD; Sarah I. Bean, MPH; Jennifer S. Lin, MD, MCR
VIEWPOINT
The Epidemiology of Firearm Injuries in the US: The Need for Comprehensive, Real-time, Actionable Data
Elinore J. Kaufman, MD, MSHP; M. Kit Delgado, MD, MS
Audio Author Interview: Approaches to Reducing Firearm Violence
Video: Approaches to Reducing Firearm Violence
Editorial: The Unrelenting Epidemic of Firearm Violence; Phil B. Fontanarosa, MD, MBA; Kirsten Bibbins-Domingo, PhD, MD, MAS
Firearms, Suicide, and Approaches for Prevention
Marian E. Betz, MD, MPH; Arielle C. Thomas, MD, MPH; Joseph A. Simonetti, MD, MPH
Homicides Involving American Indian and Alaska Native Individuals
Lori McPherson, JD
Violence and the Carceral State: A Public Health Continuum
Roger A. Mitchell Jr, MD; Jay D. Aronson, PhD
The Business Case for Reducing Firearm Injuries
Zirui Song, MD, PhD
The Supreme Court Expands Second Amendment Rights as the Nation Experiences Historic Levels of Firearms Violence
Daniel W. Webster, ScD, MPH; Lawrence O. Gostin, JD
State Firearm Laws and Firearm-Related Mortality and Morbidity
Sandro Galea, MD, DrPH; Salma M. Abdalla, MBBS, DrPH
Regulating Assault Weapons and Large-Capacity Magazines for Ammunition
Philip J. Cook, PhD; John J. Donohue, PhD, JD
Coordinating a National Approach to Violence Prevention
Joseph V. Sakran, MD, MPH, MPA; Stephen Hargarten, MD, MPH; Frederick P. Rivara, MD, MPH
The Role of Academic Medical Centers in the Prevention of Violence and Firearm-Related Morbidity and Mortality
Rebecca M. Cunningham, MD; Daniel Lee, PhD; Patrick M. Carter, MD
A New Era for Firearm Violence Prevention Research
Andrew R. Morral, PhD; Rosanna Smart, PhD
A PIECE OF MY MIND
Expanding Moral Injury: Why Resilience Training Won’t Fix It
Christian Anthony Archer, MD
EDITORIAL
The Unrelenting Epidemic of Firearm Violence
Phil B. Fontanarosa, MD, MBA; Kirsten Bibbins-Domingo, PhD, MD, MAS
Respiratory Support in the Time of COVID-19
Alistair D. Nichol, PhD; Cecilia O’Kane, PhD; Daniel F. McAuley, MD
Serplulimab With Chemotherapy in Extensive-Stage SCLC
Noura J. Choudhury, MD; Gregory J. Riely, MD, PhD
Left Ventricular Assist Devices in Advanced Heart Failure
Mark H. Drazner, MD, MSc
The Critical Need to Modernize Syphilis Screening
Susan Tuddenham, MD, MPH; Khalil G. Ghanem, MD, PhD
MEDICAL NEWS & PERSPECTIVES
Examining the Impact of Firearm Safety Laws on Suicides
Rita Rubin, MA
Audio Author Interview: Approaches to Reducing Firearm Violence
Video: Approaches to Reducing Firearm Violence
Editorial: The Unrelenting Epidemic of Firearm Violence; Phil B. Fontanarosa, MD, MBA; Kirsten Bibbins-Domingo, PhD, MD, MAS
Quick Uptakes
Physicians and EMS Who Responded to Mass Shootings Develop Consensus Recommendations for Improving Care
Kate Ruder
After the Genome—A Brief History of Proteomics
Melissa Suran, PhD, MSJ
Audio: September 2022 Medical News Summary
NEWS FROM THE CENTERS FOR DISEASE CONTROL AND PREVENTION
Long-term Household Contamination With Monkeypox Virus Investigated
Bridget M. Kuehn, MSJ
Bus and Urban Transit Workers Have Highest COVID-19 Risk
Bridget M. Kuehn, MSJ
Interim Guidance for Monkeypox Among Patients With HIV
Bridget M. Kuehn, MSJ
CLINICAL TRIALS UPDATE
Repurposed Drugs Failed to Prevent Severe COVID-19
Anita Slomski
Standing Desks Reduced Office Workers’ Sitting Time
Anita Slomski
Ketamine Noninferior to Fentanyl for Surgical Abortion Sedation
Anita Slomski
Mepolizumab Cuts Asthma Exacerbations Among High-risk Kids
Anita Slomski
HEALTH AGENCIES UPDATE
Updated Rating System for Nursing Homes
Melissa Suran, PhD, MSJ
Negative Childhood Experiences and Premature Adulthood Mortality
Melissa Suran, PhD, MSJ
Asthma and Oil Spill Cleanup
Melissa Suran, PhD, MSJ
POETRY AND MEDICINE
The Laugh
Eunice Cho, BS
JAMA REVISITED
Foreign Letters: London
JAMA PATIENT PAGE
Firearm Violence in the US
Kristin Walter, MD, MS
Screening for Syphilis
Jill Jin, MD, MPH
AUDIO
Audio Editors' Summary
Theme Issue on Firearms and Violence, Featuring Viewpoints, Editorials, Medical News, and more
Audio Author Interview
USPSTF Recommendation: Syphilis Screening in Nonpregnant Adolescents and Adults
Audio Author Interview
Approaches to Reducing Firearm Violence
Audio
September 2022 Medical News Summary
VIDEO
Approaches to Reducing Firearm Violence
COMMENT & RESPONSE
Ischemic Stroke in Patients With Asymptomatic Severe Carotid Stenosis Without Surgical Intervention
Antonio V. Sterpetti, MD; Vittorio Arici, MD; Antonio Bozzani, MD
Ischemic Stroke in Patients With Asymptomatic Severe Carotid Stenosis Without Surgical Intervention
Kuo-Wei Huang, MD; Chih-Wei Chen, MPhil; James Cheng-Chung Wei, MD, PhD
Ischemic Stroke in Patients With Asymptomatic Severe Carotid Stenosis Without Surgical Intervention
Kosmas I. Paraskevas, MD
Ischemic Stroke in Patients With Asymptomatic Severe Carotid Stenosis Without Surgical Intervention—Reply
Robert W. Chang, MD; Mai N. Nguyen-Huynh, MD; Andrew L. Avins, MD
Effect of Robot-Assisted Radical Cystectomy vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients With Bladder Cancer
Ganesh Sivarajan, MD; Murtaza Akhter, MD
Effect of Robot-Assisted Radical Cystectomy vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients With Bladder Cancer—Reply
James W. F. Catto, PhD; Pramit Khetrapal, PhD; Gareth Ambler, PhD; et al.
JAMA MASTHEAD
JAMA
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