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IN THIS ISSUE OF JAMA
Audio Highlights
Audio Editors' Summary: Subclinical Afib Detection After Stroke, Reduced vs High-Dose Glucocorticoids for ANCA-Associated Vasculitis, Review of Peripheral Arterial Disease, and more
ORIGINAL INVESTIGATION
Effect of Implantable vs Prolonged External Electrocardiographic Monitoring on Atrial Fibrillation Detection in Patients With Ischemic Stroke: The PER DIEM Randomized Clinical Trial
Brian H. Buck, MD, MSc; Michael D. Hill, MD; F. Russell Quinn, MD; et al.
Earn CME credit
Editorial: Detection of Subclinical Atrial Fibrillation After Stroke: Is There Enough Evidence to Treat?; David Tirschwell, MD, MSc; Nazem Akoum, MD, MS
Effect of Long-term Continuous Cardiac Monitoring vs Usual Care on Detection of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease: The STROKE-AF Randomized Clinical Trial
Richard A. Bernstein, MD, PhD; Hooman Kamel, MD; Christopher B. Granger, MD; et al.
Editorial: Detection of Subclinical Atrial Fibrillation After Stroke: Is There Enough Evidence to Treat?; David Tirschwell, MD, MSc; Nazem Akoum, MD, MS
Effect of Reduced-Dose vs High-Dose Glucocorticoids Added to Rituximab on Remission Induction in ANCA-Associated Vasculitis: A Randomized Clinical Trial
Shunsuke Furuta, MD, PhD; Daiki Nakagomi, MD, PhD; Yoshihisa Kobayashi, MD, PhD; et al.
Earn CME credit
RESEARCH LETTER
Antibody Response to 2-Dose SARS-CoV-2 mRNA Vaccine Series in Solid Organ Transplant Recipients
Brian J. Boyarsky, MD, PhD; William A. Werbel, MD; Robin K. Avery, MD; et al.
Earn CME credit
Concentration of Patient Care Among Buprenorphine-Prescribing Clinicians in the US
Bradley D. Stein, MD, PhD; Brendan Saloner, PhD; Megan S. Schuler, PhD; et al.
VIEWPOINT
Reconceptualizing How to Support Surrogates Making Medical Decisions for Critically Ill Patients
J. Nicholas Dionne-Odom, PhD, RN; Douglas B. White, MD, MAS
Implementing Measurement Science for Electronic Health Record Use
Edward R. Melnick, MD, MHS; Christine A. Sinsky, MD; Harlan M. Krumholz, MD, SM
An Evolving Hospital Quality Star Rating System From CMS: Aligning the Stars
Karl Y. Bilimoria, MD, MS; Cynthia Barnard, PhD, MBA
Does Sleep Flush Wastes From the Brain?
Anthony L. Komaroff, MD
A PIECE OF MY MIND
The Challenge of Knowing
Jessica Kalender-Rich, MD
EDITORIAL
Detection of Subclinical Atrial Fibrillation After Stroke: Is There Enough Evidence to Treat?
David Tirschwell, MD, MSc; Nazem Akoum, MD, MS
REVIEW
Lower Extremity Peripheral Artery Disease Without Chronic Limb-Threatening Ischemia: A Review
Tamar S. Polonsky, MD, MSCI; Mary M. McDermott, MD
Earn CME credit
Audio Clinical Review: Lower Extremity Peripheral Artery Disease Without Chronic Limb-Threatening Ischemia
JAMA INSIGHTS
Mask Mandates, On-Premises Dining, and COVID-19
Gery P. Guy Jr, PhD, MPH; Greta M. Massetti, PhD; Erin Sauber-Schatz, PhD, MPH
Earn CME credit
Reactogenicity Following Receipt of mRNA-Based COVID-19 Vaccines
Johanna Chapin-Bardales, PhD, MPH; Julianne Gee, MPH; Tanya Myers, PhD, MSc
Earn CME credit
MEDICAL NEWS & PERSPECTIVES
Lead, Mistrust, and Trauma—Whistleblowing Pediatrician Discusses the Legacy of Flint’s Water Crisis
Jennifer Abbasi
JAMA Medical News Audio: Whistleblower Pediatrician Discusses the Legacy of Flint, Michigan’s Water Crisis
Start-ups Tout Continuous Glucose Monitoring for People Without Diabetes
Mary Chris Jaklevic, MSJ
NEWS FROM THE FOOD AND DRUG ADMINISTRATION
Immunotherapy Approved for Endometrial Cancer
Rebecca Voelker, MSJ
Helping Patients Improve Muscle Movement After Stroke
Rebecca Voelker, MSJ
New Naloxone Dosage Is Approved
Rebecca Voelker, MSJ
POETRY AND MEDICINE
Prayer Whistle in the SARS-CoV-2 Ward
Nuria M. Pastor-Soler, MD, PhD
JAMA REVISITED
Selections
JAMA PATIENT PAGE
Atrial Fibrillation
Jayson R. Baman, MD; Rod S. Passman, MD, MSCE
AUDIO
Audio Editors' Summary
Subclinical Afib Detection After Stroke, Reduced vs High-Dose Glucocorticoids for ANCA-Associated Vasculitis, Review of Peripheral Arterial Disease, and more
Audio Clinical Review
Lower Extremity Peripheral Artery Disease Without Chronic Limb-Threatening Ischemia
COMMENT & RESPONSE
Risks and Benefits of Benzodiazepines
Mark Abie Horowitz, MBBS, PhD; James M. Wright, MD, PhD; David Taylor, PhD
Risks and Benefits of Benzodiazepines
Utsav Shrestha, MD; Reena Karnik, MD; Niva Joshi, BSc
Risks and Benefits of Benzodiazepines—Reply
Matthew E. Hirschtritt, MD, MPH; Mark Olfson, MD, MPH; Kurt Kroenke, MD
APOE Allele Testing and Alzheimer Disease
Mu-Hong Chen, MD, PhD; Fu-Chi Yang, MD, PhD; Chih-Sung Liang, MD
APOE Allele Testing and Alzheimer Disease—Reply
Parichita Choudhury, MD, MSc; Vijay K. Ramanan, MD, PhD; Bradley F. Boeve, MD
CORRECTION
Incorrect Data in Table
JAMA MASTHEAD
JAMA
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