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IN THIS ISSUE OF JAMA
Audio Highlights
Audio: Aspirin for Breast Cancer, Smoking Cessation After Initial Treatment Failure, Mortality Disparities Among US Youth, and more
ORIGINAL INVESTIGATION
Aspirin vs Placebo as Adjuvant Therapy for Breast Cancer: The Alliance A011502 Randomized Trial
Wendy Y. Chen, MD; Karla V. Ballman, PhD; Ann H. Partridge, MD; et al.
Editorial: The Aspirin Conundrum—Navigating Negative Results, Age, Aging Dynamics, and Equity ; Jeanne S. Mandelblatt, MD, MPH; Candace Mainor, MD; Barry I. Hudson, PhD
Smoking Cessation After Initial Treatment Failure With Varenicline or Nicotine Replacement: A Randomized Clinical Trial
Paul M. Cinciripini, PhD; Charles E. Green, PhD; Sanjay Shete, PhD; et al.
Audio: Smoking Cessation After Initial Treatment Failure With Varenicline or Nicotine Replacement
Racial and Ethnic Disparities in All-Cause and Cause-Specific Mortality Among US Youth
Elizabeth R. Wolf, MD, MPH; Frederick P. Rivara, MD, MPH; Colin J. Orr, MD, MPH; et al.
Audio: Racial and Ethnic Disparities in All-Cause and Cause-Specific Mortality Among US Youth
Editorial: Injury Prevention Science and Firearm Injury in Pediatric Health ; Patrick M. Carter, MD; Laura Seewald, MD; Marc Zimmerman, PhD
Youth Experiencing Parental Death Due to Drug Poisoning and Firearm Violence in the US, 1999-2020
Benjamin-Samuel Schlüter, PhD; Diego Alburez-Gutierrez, PhD; Kirsten Bibbins-Domingo, PhD, MD, MAS; et al.
RESEARCH LETTER
Global Production of Active Pharmaceutical Ingredients for US Generic Drugs Experiencing Shortages
Mariana P. Socal, MD, PhD; Matthew A. Crane, BS; Gerard F. Anderson, PhD
Health and the 2024 US Election
Race and Ethnicity of Reproductive-Age Females Affected by US State Abortion Bans
Demetri Goutos, MBA; Nina Cesare, PhD; Cecilia Vu, PhD, MPH; et al.
VIEWPOINT
At-Home Diagnostics Solutions for Chlamydia and Gonorrhea
Ellen N. Kersh, PhD; Leandro A. Mena, MD
Urgent Need for Regulatory Oversight of Human Cells, Tissues, and Cellular and Tissue–Based Products
Robert P. Dickson, MD; Deborah A. Dingell, MS
The FDA and Gene Therapy for Duchenne Muscular Dystrophy
David M. Rind, MD
A PIECE OF MY MIND
My Digital Refuge
Anna Wexler, PhD
EDITORIAL
The Aspirin Conundrum—Navigating Negative Results, Age, Aging Dynamics, and Equity
Jeanne S. Mandelblatt, MD, MPH; Candace Mainor, MD; Barry I. Hudson, PhD
Injury Prevention Science and Firearm Injury in Pediatric Health
Patrick M. Carter, MD; Laura Seewald, MD; Marc Zimmerman, PhD
Audio: Racial and Ethnic Disparities in All-Cause and Cause-Specific Mortality Among US Youth
REVIEW
Women's Health
The Women’s Health Initiative Randomized Trials and Clinical Practice: A Review
JoAnn E. Manson, MD, DrPH; Carolyn J. Crandall, MD, MS; Jacques E. Rossouw, MD; et al.
Earn CME credit
JAMA INSIGHTS
Climate Change and Health
Climate Change and Mental Health
Susan Clayton, PhD; Lily A. Brown, PhD
Earn CME credit
EDITOR'S NOTE
Illness, Isolation, and the Poetry of Illumination
Rafael Campo, MD, MA
MEDICAL NEWS & PERSPECTIVES
AI in Medicine
One Day, AI Could Mean Better Mental Health for All
Jennifer Abbasi; Yulin Hswen, ScD, MPH
Audio: Enhancing Global Mental Health Care With Digital Tools and AI for Scalable Interventions
Multidrug-Resistant “Super Gonorrhea” Rallies Multipronged Effort
Esther Wei-Yun Landhuis, PhD
MEDICAL NEWS IN BRIEF
β-Blockers After Heart Attacks Might Not Lower Deaths for Some
Emily Harris
Oral Drug as Effective as Topical Cream for Male Pattern Baldness
Emily Harris
Deaths of Despair Surged Among Black People Over Past Decade
Emily Harris
Prostate Cancer Cases Might Rise to 3 Million Globally by 2040
Emily Harris
Swapping Salt for a Substitute May Lower Deaths, Reduce Heart Problems
Emily Harris
Encouraging Exercise Through Games, Money Built Long-Term Habits
Emily Harris
Meta-Analysis: Touch Tied to Improved Mental, Physical Health
Emily Harris
Therapeutic Psilocybin's Adverse Effects Mostly Resolved Within 2 Days
Emily Harris
Young Patients Without Genetic Risk Have Low Chance of Second Breast Cancer
Emily Harris
POETRY AND MEDICINE
After the Diagnosis, You Find a Moth
Judith Harris
Editor's Note: Illness, Isolation, and the Poetry of Illumination ; Rafael Campo, MD, MA
JAMA REVISITED
Acronymity: Henry T. Ricketts, MD, Contributing Editor
JAMA PATIENT PAGE
What Is Strep Throat?
Cari H. Rayborn, MD; Christopher D. Jackson, MD; Nathan A. Summers, MD
AUDIO
Editor's Summary Audio
Aspirin for Breast Cancer, Smoking Cessation After Initial Treatment Failure, Mortality Disparities Among US Youth, and more
Author Interviews Audio
Smoking Cessation After Initial Treatment Failure With Varenicline or Nicotine Replacement
Author Interviews Audio
Racial and Ethnic Disparities in All-Cause and Cause-Specific Mortality Among US Youth
Medical News Audio
Enhancing Global Mental Health Care With Digital Tools and AI for Scalable Interventions
COMMENT & RESPONSE
Recurrent Gout and Serum Urate
Kuochen Chang, MD; Shunfa Hung, MD
Recurrent Gout and Serum Urate
Dan Shan, MSc
Recurrent Gout and Serum Urate—Reply
Natalie McCormick, PhD; Hyon K. Choi, MD, DrPH
Outcomes Following Localized Prostate Cancer Treatment
Tian-bao Huang, MD; Xue-fei Ding, MD, PhD
Outcomes Following Localized Prostate Cancer Treatment
Jean-Nicolas Cornu, MD, PhD
Outcomes Following Localized Prostate Cancer Treatment—Reply
Daniel A. Barocas, MD, MPH; Bashir Al Hussein Al Awamlh, MD; Tatsuki Koyama, PhD
CORRECTION
Incorrect Degree
Table Data Errors
JAMA MASTHEAD
JAMA
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