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IN THIS ISSUE OF JAMA
Audio Highlights
Audio: Oxygen Saturation Targets After Out-of-Hospital Cardiac Arrest, Mental Health Outcomes Following Extracorporeal Membrane Oxygenation, Preoperative Hemodialysis Timing, and more
ORIGINAL INVESTIGATION
Effect of Lower vs Higher Oxygen Saturation Targets on Survival to Hospital Discharge Among Patients Resuscitated After Out-of-Hospital Cardiac Arrest: The EXACT Randomized Clinical Trial
Stephen A. Bernard, MD; Janet E. Bray, PhD; Karen Smith, PhD; et al.
Editorial: Early Oxygen Supplementation After Resuscitation From Cardiac Arrest; Jonathan Elmer, MD, MS; Francis X. Guyette, MD, MPH, MS
Caring for the Critically Ill Patient
Association of Extracorporeal Membrane Oxygenation With New Mental Health Diagnoses in Adult Survivors of Critical Illness
Shannon M. Fernando, MD, MSc; Mary Scott, MSc; Robert Talarico, MSc; et al.
Editorial: Mental Health Outcomes Following Extracorporeal Membrane Oxygenation in Survivors of Critical Illness; Marieke Zegers, PhD; Mark van den Boogaard, RN, PhD; J. G. (Hans) van der Hoeven, MD, PhD
Association Between Preoperative Hemodialysis Timing and Postoperative Mortality in Patients With End-stage Kidney Disease
Vikram Fielding-Singh, MD, JD; Matthew W. Vanneman, MD; Tristan Grogan, MS; et al.
Editorial: Optimal Timing of Hemodialysis Before Surgery; Anthony J. Bleyer, MD, MS
RESEARCH LETTER
Trends in Urinary Biomarkers of Exposure to Nicotine and Carcinogens Among Adult e-Cigarette Vapers vs Cigarette Smokers in the US, 2013-2019
Hongying Daisy Dai, PhD; Adam M. Leventhal, PhD; Ali S. Khan, MD, MPH
Trends in the Association Between Diabetes and Cardiovascular Events, 1994-2019
Calvin Ke, MD, PhD; Lorraine L. Lipscombe, MD, MSc; Alanna Weisman, MD, PhD; et al.
VIEWPOINT
Addressing Gaps in Research to Reduce Disparities and Advance Health Equity: The USPSTF Incorporation of the NASEM Taxonomy on Closing Evidence Gaps in Clinical Prevention
Carol M. Mangione, MD, MSPH; Wanda Nicholson, MD, MPH; Karina W. Davidson, PhD, MASc
Hospital Rankings and Health Equity
Tavia Binger, MSPH; Harold Chen, BA; Ben Harder, BA
Reforming the World Health Organization’s Essential Medicines List: Essential but Unaffordable
Thomas J. Hwang, MD; Aaron S. Kesselheim, MD, JD, MPH; Kerstin N. Vokinger, MD, JD, PhD
A PIECE OF MY MIND
The Value of a Gut Punch
Kyle E. Karches, MD, PhD
EDITORIAL
Early Oxygen Supplementation After Resuscitation From Cardiac Arrest
Jonathan Elmer, MD, MS; Francis X. Guyette, MD, MPH, MS
Mental Health Outcomes Following Extracorporeal Membrane Oxygenation in Survivors of Critical Illness
Marieke Zegers, PhD; Mark van den Boogaard, RN, PhD; J. G. (Hans) van der Hoeven, MD, PhD
Optimal Timing of Hemodialysis Before Surgery
Anthony J. Bleyer, MD, MS
REVIEW
Treatment of Hypertension: A Review
Robert M. Carey, MD; Andrew E. Moran, MD; Paul K. Whelton, MB, MD, MSc
Earn CME credit
Audio: Treatment of Hypertension in 2022
JAMA INSIGHTS
Clinical Update
Diagnosis and Management of Hereditary Hemochromatosis
Elizabeth Cabrera, MD; Gonzalo Crespo, MD; Lisa B. VanWagner, MD, MSc
Earn CME credit
MEDICAL NEWS & PERSPECTIVES
EPA Takes Action Against Harmful “Forever Chemicals” in the US Water Supply
Melissa Suran, PhD, MSJ
NEWS FROM THE CENTERS FOR DISEASE CONTROL AND PREVENTION
Shifting Hepatitis A Epidemiology Requires Renewed Vaccination Efforts
Bridget M. Kuehn, MSJ
Second COVID-19 Booster Increases Protection for Nursing Home Patients
Bridget M. Kuehn, MSJ
Single Monkeypox Vaccine Dose Provides Some Protection
Bridget M. Kuehn, MSJ
BIOTECH INNOVATIONS
Gene Therapy for Sickle Cell Disease, β-Thalassemia Enters Regulatory Reviews
Howard D. Larkin
Noninvasive Neuromodulation May Help Improve Function in Cerebral Palsy
Howard D. Larkin
Bionic Pancreas Outperforms Standard Care for Type 1 Diabetes in Trial
Howard D. Larkin
POETRY AND MEDICINE
The End
Jim Johnstone
JAMA REVISITED
Current Comment
JAMA PATIENT PAGE
What Is Hereditary Hemochromatosis?
Kristin Walter, MD, MS
AUDIO
Audio Editor’s Summary
Oxygen Saturation Targets After Out-of-Hospital Cardiac Arrest, Mental Health Outcomes Following Extracorporeal Membrane Oxygenation, Preoperative Hemodialysis Timing, and more
Clinical Reviews Audio
Treatment of Hypertension in 2022
COMMENT & RESPONSE
Outcomes From Intraoperative Handovers of Anesthesia Care
Philip M. Jones, MD, MSc; Louise Y. Sun, MD, SM; Michael J. Brenner, MD
Outcomes From Intraoperative Handovers of Anesthesia Care
Andrea Vannucci, MD, MS; Steven Greenberg, MD; Matthew B. Weinger, MD, MS
Outcomes From Intraoperative Handovers of Anesthesia Care—Reply
Melanie Meersch, MD; Daniel I. Sessler, MD; Alexander Zarbock, MD
Racial and Ethnic Differences in Resident Selection
Daryl Turner, DO; Murtaza Akhter, MD
Racial and Ethnic Differences in Resident Selection—Reply
Randall A. Bly, MD; Mark E. Whipple, MD, ScM; Sarah N. Bowe, MD, EdM
CORRECTION
Clarification of Wording in Medical News Interview
Contributor Name Misspelled
JAMA MASTHEAD
JAMA
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