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JAMA Internal Medicine New Issue September 2025; Volume 185, Number 9

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New Issue

September 2025; Volume 185, Number 9
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Viewpoint

The Rapid Spread of a Novel Adulterant in the US Illicit Drug Supply—BTMPS

David T. Zhu, BSc; Alex J. Krotulski, PhD; Joseph J. Palamar, PhD

Women's Health

From Breast Cancer Screening to Diagnosis: New Recommendations for Expanded Coverage and Patient Navigation

Catherine T. Witkop, MD, PhD, MPH; Heidi D. Nelson, MD, MPH

Managing Anticancer Drug Spending in Medicare

Stacie B. Dusetzina, PhD

Inside Story

Physician Work Environment and Well-Being

Accepting Accommodations—Disability in Medical Training

Romila Santra, MA

Women's Health

Moving Through Grief—How Loss Transformed My Science

Emily E. Haroz, MA, MHS, PhD

Original Investigation

Cannabidiol and Liver Enzyme Level Elevations in Healthy Adults: A Randomized Clinical Trial

Jeffry Florian, PhD; Pablo Salcedo, MD; Keith Burkhart, MD; et al.

Editorial: Elevated Concerns About Cannabidiol and Liver Enzymes; Nathan M. Stall, MD, PhD; Kenneth E. Covinsky, MD, MPH

Clinical Decision Support System for Primary Care of Opioid Use Disorder: A Randomized Clinical Trial

Rebecca C. Rossom, MD, MS; A. Lauren Crain, PhD; Eric A. Wright, PharmD; et al.

Metformin and Time to Sustained Recovery in Adults With COVID-19: The ACTIV-6 Randomized Clinical Trial

Carolyn T. Bramante, MD, MPH; Thomas G. Stewart, PhD; David R. Boulware, MD, MPH; et al.

Frequent Missed Opportunities for Earlier Diagnosis of Advanced-Stage Colorectal or Lung Cancer

Andrew J. Zimolzak, MD, MMSc; Paarth Kapadia, MD; Divvy K. Upadhyay, MD, MPH, CPHRM, CPPS; et al.

Aging and Health

The Patient Driven Payment Model, Skilled Nursing Facility Coding Intensity, and Medicare Expenditures

Fangli Geng, PhD; Xinran Lu, MS; Elizabeth M. White, PhD, APRN; et al.

Health Equity

Self-Collection for Cervical Cancer Screening in a Safety-Net Setting: The PRESTIS Randomized Clinical Trial

Jane R. Montealegre, PhD; Susan G. Hilsenbeck, PhD; Shaun Bulsara, MS; et al.

Editorial: HPV Self-Collection for Cervical Cancer Screening—There’s No Place Like Home; Eve Rittenberg, MD, MA; Ilana B. Richman, MD, MHS; Giselle Corbie, MD, MSc; Cary P. Gross, MD; Ishani Ganguli, MD, MPH

Germicidal UV Light and Incidence of Acute Respiratory Infection in Long-Term Care for Older Adults: A Randomized Clinical Trial

Andrew P. Shoubridge, PhD; Amanda Brass, PhD; Maria Crotty, MBBS; et al.

Nurse-Led Family Support Intervention for Families of Critically Ill Patients: The FICUS Cluster Randomized Clinical Trial

Rahel Naef, PhD, RN; Marie-Madlen Jeitziner, PhD, RN; Marco Riguzzi, PhD; et al.

Editor's Note: Supporting Families in the Adult Intensive Care Unit With High Touch-Low Tech Interventions; Nathan M. Stall, MD, PhD; Lona Mody, MD, MSc

Editorial

Elevated Concerns About Cannabidiol and Liver Enzymes

Nathan M. Stall, MD, PhD; Kenneth E. Covinsky, MD, MPH

HPV Self-Collection for Cervical Cancer Screening—There’s No Place Like Home

Eve Rittenberg, MD, MA; Ilana B. Richman, MD, MHS; Giselle Corbie, MD, MSc; et al.

Invited Commentary

Increasing Opioid Use Disorder Medication Treatment in Primary Care—What Works?

Katharine A. Bradley, MD, MPH; Helen E. Jack, MD; Claire B. Simon, MD

Medicare’s Patient Driven Payment Model for Skilled Nursing Facilities—Getting What We Pay For

Kira L. Ryskina, MD, MSHP; Ye Tian, MD

Can Upper-Room UV Light Prevent Nosocomial Respiratory Viral Infections?

Michael Klompas, MD, MPH

Roots of Disability Discrimination in Medical Schools

Lisa I. Iezzoni, MD, MSc; Carol Haywood, PhD, OTR/L

Editor's Note

Supporting Families in the Adult Intensive Care Unit With High Touch-Low Tech Interventions

Nathan M. Stall, MD, PhD; Lona Mody, MD, MSc

Out-of-Sequence Allocation of Deceased Donor Kidneys—When Discretion Undermines Equity

Giselle Corbie, MD, MSc; Jerard Z. Kneifati-Hayek, MD, MS; Raegan W. Durant, MD, MPH

Research Letter

Socioeconomic Disparities in Out-of-Sequence Placement of Deceased Donor Kidneys in the US

Sumit Mohan, MD, MPH; Miko E. Yu, MA; Joel T. Adler, MD; et al.

Editor's Note: Out-of-Sequence Allocation of Deceased Donor Kidneys—When Discretion Undermines Equity; Giselle Corbie, MD, MSc; Jerard Z. Kneifati-Hayek, MD, MS; Raegan W. Durant, MD, MPH

Oncology “Me-Too” Drugs Compared With Original Drugs in Randomized Clinical Trials

Timothée Olivier, MD; Calvin Smith, BS; Vinay Prasad, MD, MPH; et al.

Safety of Vancomycin Use Through Midline Catheters for Outpatient Parenteral Antimicrobial Therapy

David Paje, MD, MPH; Emily Walzl, MS; Megan Heath, PhD; et al.

Prevalence and Sources of Disability-Based Discrimination in a National Sample of Graduating Medical Students

Mytien Nguyen, MS; Justin L. Bullock, MD, MPH; Karina Pereira-Lima, PhD, MSc; et al.

Clinical Insights

Integrating Diet and Physical Activity When Prescribing GLP-1s—Lifestyle Factors Remain Crucial

Farhad Mehrtash, MPH; Jody Dushay, MD, MMSc; JoAnn E. Manson, MD, DrPH

Earn CME credit

Guide to Statistics and Methods

Covariate-Constrained Randomization

Jody D. Ciolino, PhD; Jacob M. Schauer, PhD; Lauren B. Bonner, PhD

Earn CME credit

Challenges in Clinical Electrocardiography

An Unusual Cause of Atrioventricular Block

Kapil Rajendran, MD, DM; Arun Jude Alphonse, MD, DM; Vinayakumar Desabandhu, MD, DM

Earn CME credit

JAMA Internal Medicine Patient Page

I Am Taking a GLP-1 Weight-Loss Medication—What Should I Know?

Farhad Mehrtash, MPH; Jody Dushay, MD, MMSc; JoAnn E. Manson, MD, DrPH

Comment & Response

Is Patient-Centered Advance Care Planning Truly Effective?

Yu Xiaoyan, RN; Xiao Weiwei, RN

Aging and Health

Impact of Antivirals in Nonsevere Influenza Remains Unclear

Marilyn N. Bulloch, PharmD, BCPS

Editor's Note: The Limited Role for Antiviral Therapy in Influenza; Jonathan D. Baghdadi, MD; Deborah Grady, MD, MPH; Daniel J. Morgan, MD, MS

Impact of Antivirals in Nonsevere Influenza Remains Unclear—Reply

Ya Gao, PhD; Gordon Guyatt, MD; Qiukui Hao, MD

Improving Research Design in Long-Term Opioid Management

Kwok Ying Chan, MD, MBChB; Chi Wing Timmy Chan, MBBS

Improving Research Design in Long-Term Opioid Management—Reply

Erin E. Krebs, MD, MPH; David B. Nelson, PhD

Physician Work Environment and Well-Being

Male Physicians’ Mortality Advantage and the “Crisis of Boys and Men”

Teva D. Brender, MD; Elizabeth W. Dzeng, MD, PhD, MPH

Male Physicians’ Mortality Advantage and the “Crisis of Boys and Men”—Reply

Vishal R. Patel, MD, MPH; Christopher M. Worsham, MD, MPH; Anupam B. Jena, MD, PhD

Study Limitations in Statin Use and Risk of Hepatocellular Carcinoma

Ishak A. Mansi, MD

Study Limitations in Statin Use and Risk of Hepatocellular Carcinoma—Reply

Jonggi Choi, MD, PhD; Raymond T. Chung, MD

MOSAAIC to Capture Key Measures of Aging Across the Lifespan

Alka M. Kanaya, MD; Garnet L. Anderson, PhD

Aging and Health

MOSAAIC to Capture Key Measures of Aging Across the Lifespan—Reply

Lingsheng Li, MD, MHS; Anna Chang, MD; Kenneth E. Covinsky, MD, MPH

Methodological Concerns in Post-Dobbs OBGYN Practitioner Movement Study

Becky Staiger, PhD; Julia Strasser, DrPH; Caitlin Myers, PhD

Methodological Concerns in Post-Dobbs OBGYN Practitioner Movement Study—Reply

Jane M. Zhu, MD, MPP; K. John McConnell, PhD; Maria Rodriguez, MD, MPH

Insights and Considerations for the START Trial and Managing Opioid Use Disorder

Bowen Xu, MD; Kaixuan Fu, MD; Jun Yang, MD

Insights and Considerations for the START Trial and Managing Opioid Use Disorder—Reply

Allison J. Ober, PhD; Cristina Murray-Krezan, PhD; Itai Danovitch, MD

Less Is More

The Illusion of Choice—Buprenorphine Without Implementation

Katie Fitzgerald Jones, PhD, ACHPN; Jessica S. Merlin, PhD, MD, MBA; Amy M. Linsky, MD, MSc

Editorial: Integrating Buprenorphine Into Chronic Pain Treatment—Putting the Choice in VOICE; Michael A. Incze, MD, MSEd; Timothy S. Anderson, MD, MAS

The Illusion of Choice—Buprenorphine Without Implementation—Reply

William C. Becker, MD; Karen H. Seal, MD, MPH; Erin E. Krebs, MD, MPH

Correction

Coding Error and Misclassification of Respondents

Change in Publication License

JAMA Internal Medicine Masthead

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