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VIEWPOINT
Detecting Selection Bias in Observational Studies—When Interventions Work Too Fast
Ghulam Rehman Mohyuddin, MD; Vinay Prasad, MD
Centers for Disease Control and Prevention Guideline for Prescribing Opioids, 2022—Need for Integrating Dosing Benchmarks With Shared Decision-Making
Mark D. Sullivan, MD, PhD; Jeffrey A. Linder, MD, MPH; Jason N. Doctor, PhD
Are New Alzheimer Drugs Better Than Older Drugs?
Susan Molchan, MD; Adriane Fugh-Berman, MD
PERSPECTIVE
The Deep Work of Doctoring—Prioritizing Relationships in Medicine
Elizabeth T. Toll, MD; Christine A. Sinsky, MD
The Thinker—A Work by Rodin With a Message for Clinicians
Shaurya Taran, MD
ORIGINAL INVESTIGATION
Excess Death Rates for Republican and Democratic Registered Voters in Florida and Ohio During the COVID-19 Pandemic
Jacob Wallace, PhD; Paul Goldsmith-Pinkham, PhD; Jason L. Schwartz, PhD
Temporal Clustering of Critical Illness Events on Medical Wards
Samik Doshi, MD, MSc; Saeha Shin, MPH; Lauren Lapointe-Shaw, MD, PhD; et al.
Editorial: Intensive Care Unit Transfer Decisions—Science or Art? ; Tracy Y. Wang, MD, MHS, MSc; Tyrone A. Johnson, MD; Mitchell H. Katz, MD
A Statewide Quality Initiative to Reduce Unnecessary Antibiotic Treatment of Asymptomatic Bacteriuria
Valerie M. Vaughn, MD, MSc; Ashwin Gupta, MD; Lindsay A. Petty, MD; et al.
Efficacy of a Clinical Decision Rule to Enable Direct Oral Challenge in Patients With Low-Risk Penicillin Allergy : The PALACE Randomized Clinical Trial
Ana Maria Copaescu, MD; Sara Vogrin, MBiostat; Fiona James, BBiomedSci; et al.
Association of Social Isolation With Hospitalization and Nursing Home Entry Among Community-Dwelling Older Adults
Mary Louise Pomeroy, PhD, MPH; Thomas K. M. Cudjoe, MD, MPH; Alison E. Cuellar, PhD; et al.
Health Care Policy and Law
National Estimates of the Adult Diabetes Care Continuum in India, 2019-2021
Jithin Sam Varghese, PhD; Ranjit Mohan Anjana, MD, PhD; Pascal Geldsetzer, MD, PhD; et al.
Aortic Stenosis Risk in Rheumatoid Arthritis
Tate M. Johnson, MD; Chetaj A. Mahabir, MBBS; Yangyuna Yang, MBBS, PhD; et al.
Prospective Associations of Different Combinations of Aerobic and Muscle-Strengthening Activity With All-Cause, Cardiovascular, and Cancer Mortality
Rubén López-Bueno, PhD; Matthew Ahmadi, PhD; Emmanuel Stamatakis, PhD; et al.
Author Interviews Audio: Prospective Associations of Aerobic and Muscle-Strengthening Activity With Mortality
Silicosis Among Immigrant Engineered Stone (Quartz) Countertop Fabrication Workers in California
Jane C. Fazio, MD; Sheiphali A. Gandhi, MD, MPH; Jennifer Flattery, MPH; et al.
Editorial: Engineered Stone–Associated Silicosis—A Lethal Variant of an Ancient Disease; Jeremy T. Hua, MD, MPH; Cecile S. Rose, MD, MPH; Carrie A. Redlich, MD, MPH
Author Interviews Audio: Silicosis Among Immigrant Engineered Stone (Quartz) Countertop Fabrication Workers in California
EDITORIAL
Engineered Stone–Associated Silicosis—A Lethal Variant of an Ancient Disease
Jeremy T. Hua, MD, MPH; Cecile S. Rose, MD, MPH; Carrie A. Redlich, MD, MPH
Author Interviews Audio: Silicosis Among Immigrant Engineered Stone (Quartz) Countertop Fabrication Workers in California
Health Care Policy and Law
Statutory Authority for Medicare Coverage Decisions—CMS Is an Independent Federal Agency
Francis X. Crosson, MD; Rita F. Redberg, MD, MSc
Strategies to Promote High-Value, Evidence-Based Pharmaceuticals
Joshua Hauser, BS; Rita F. Redberg, MD, MSc
Intensive Care Unit Transfer Decisions—Science or Art?
Tracy Y. Wang, MD, MHS, MSc; Tyrone A. Johnson, MD; Mitchell H. Katz, MD
Announcing Expanded Content for Clinicians Through the Clinical Review and Education Section at JAMA Internal Medicine
Michael A. Incze, MD, MSEd; Deborah Grady, MD, MPH; Sharon K. Inouye, MD, MPH
INVITED COMMENTARY
Increasing Evidence That Diagnostic Stewardship May Improve Antibiotic Use
Daniel J. Morgan, MD, MS; Surbhi Leekha, MBBS, MPH; Kimberly C. Claeys, PharmD, PhD
The Penicillin Allergy Decision Rule—Something New for Penicillin Allergy
Allison Ramsey, MD; S. Shahzad Mustafa, MD
EDITOR'S NOTE
Opioid Dosing by Primary Care Professionals—A Call for Humility
Mitchell H. Katz, MD; Deborah Grady, MD
Evolving Methods to Assess Chatbot Performance in Health Sciences Research
Eric Ward, MD; Cary Gross, MD
SPECIAL COMMUNICATION
Health Care Policy and Law
Authority of Medicare to Limit Coverage of FDA-Approved Products: Legal and Policy Considerations
C. Joseph Ross Daval, JD; Aaron S. Kesselheim, MD, JD, MPH
Earn CME credit
Editorial: Statutory Authority for Medicare Coverage Decisions—CMS Is an Independent Federal Agency; Francis X. Crosson, MD; Rita F. Redberg, MD, MSc
RESEARCH LETTER
Reports of Injection Site Necrosis After 23-Valent Pneumococcal Vaccine Use
Brendan Day, MD, MPH; Deborah Thompson, MD, MSPH; Adamma Mba-Jonas, MD, MPH; et al.
Health Care Policy and Law
Commercial Health Plan and Enrollee Out-of-Pocket Spending on Accelerated Approval Products in 2019
Shelley A. Jazowski, PhD, MPH; Avi U. Vaidya, MPH; Julie M. Donohue, PhD; et al.
Editorial: Strategies to Promote High-Value, Evidence-Based Pharmaceuticals; Joshua Hauser, BS; Rita F. Redberg, MD, MSc
Physician Work Environment and Well-Being
Psychosocial Burdens Associated With Family Building Among Physicians and Medical Students
Morgan S. Levy, BS; Amelia G. Kelly, MD; Claudia Mueller, PhD, MD; et al.
Association of Racial and Ethnic Identity With Attrition From MD-PhD Training Programs
Mytien Nguyen, MS; Elle Lett, PhD, MA; Jose E. Cavazos, MD, PhD; et al.
Health Care Policy and Law
Buprenorphine Out-of-Pocket Costs and Discontinuation in Privately Insured Adults With Opioid Use Disorder
Ashley A. Leech, PhD, MS; Elizabeth McNeer, MS; Andrew W. Roberts, PharmD, PhD; et al.
Comparison of History of Present Illness Summaries Generated by a Chatbot and Senior Internal Medicine Residents
Ashwin Nayak, MD, MS; Matthew S. Alkaitis, MD, PhD; Kristen Nayak, MD; et al.
Editor's Note: Evolving Methods to Assess Chatbot Performance in Health Sciences Research; Eric Ward, MD; Cary Gross, MD
Chatbot vs Medical Student Performance on Free-Response Clinical Reasoning Examinations
Eric Strong, MD; Alicia DiGiammarino, MS; Yingjie Weng, MHS; et al.
Editor's Note: Evolving Methods to Assess Chatbot Performance in Health Sciences Research; Eric Ward, MD; Cary Gross, MD
CHALLENGES IN CLINICAL ELECTROCARDIOGRAPHY
Migrating Localized ST-Segment Elevation With Ongoing Chest Pain
Yunling Xiao, MD; Ruihai Zhou, MSc, MD
Earn CME credit
Spiked Helmet Sign in the Inferior Leads
Yousif Al Saiegh, MD; Steven Liskov, MD; Gan-Xin Yan, MD, PhD
Earn CME credit
Ventricular Arrest With a Duration of 23.8 Seconds
Zhongzheng Zhou, MD; Yi Long, MD; Yong Li, MD
Earn CME credit
Unusual Tachycardia After Cocaine Use
Mazen M. Kawji, MD
Earn CME credit
Inverted U Waves—Red Flags in Electrocardiograms
Hui Shu, MD; Bao-jian Liao, PhD; Ding Peng, MD
Earn CME credit
AUDIO
Author Interview Audio
Prospective Associations of Aerobic and Muscle-Strengthening Activity With Mortality
Author Interview Audio
Silicosis Among Immigrant Engineered Stone (Quartz) Countertop Fabrication Workers in California
COMMENT & RESPONSE
Chief Residency—More Than Just Teaching and Scheduling
William K. Silverstein, MD, MSc; Lynfa Stroud, MD, MEd; Jonathan S. Zipursky, MD, PhD
Chief Residency—More Than Just Teaching and Scheduling—Reply
Lucy Chen, PhD; J. Michael McWilliams, MD, PhD
Another Take-Home Point for Diagnosis of New Giant T-Wave Inversions
Claudia Stöllberger, MD; Josef Finsterer, MD; Birke Schneider, MD
Less Is More
Preoperative Medical Consultation—Questioning a Long-Standing Practice
Vasu Sareen, MD; Daniel Ho, MD
Preoperative Medical Consultation—Questioning a Long-Standing Practice
Nirvik Pal, MBBS, MD; Mark Nelson, MD; John Butterworth, MD
Less Is More
Preoperative Medical Consultation—Questioning a Long-Standing Practice—In Reply
Weiwei Beckerleg, MD, MPH; Daniel I. McIsaac, MD, MPH
Vaccination After SARS-CoV-2 Infection and Post−COVID-19 Condition
Chengliang Yang, MD; Linda Lapp, PhD; Scott J. Tebbutt, PhD
Vaccination After SARS-CoV-2 Infection and Post−COVID-19 Condition—In Reply
Vasiliki Tsampasian, MD, MSc; Vassilios S. Vassiliou, MBBS, PhD
Notice of Retraction and Replacement. Goobie et al. Association of Particulate Matter Exposure With Lung Function and Mortality Among Patients With Fibrotic Interstitial Lung Disease. JAMA Intern Med . 2022;182(12):1248-1259
Gillian C. Goobie, MD, PhD; S. Mehdi Nouraie, MD, PhD
JAMA INTERNAL MEDICINE MASTHEAD
JAMA Internal Medicine
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