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JAMA Internal Medicine New Issue November 2025; Volume 185, Number 11

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New Issue

November 2025; Volume 185, Number 11
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Viewpoint

Compassionate Release Reform—Moving Medical Parole to Medical Professionals

Nicole Mushero, MD, PhD; Mark Spencer, MD

Aging and Health

Caregiving Under the Medicare Hospice Benefit

Helen P. Knight, MD; Richard E. Leiter, MD, MA; Harry J. Han, MD

Inside Story

The Quiet Part of Medicine—Caring Beyond the Protocol

Zhe Wang, MM; Dao Xin, MD; Feng Wang, MD

Confronting Medical Misinformation: Leveraging Our Pandemic Experiences

Patrick L. Johnson, MD, MPH

Original Investigation

Azelastine Nasal Spray for Prevention of SARS-CoV-2 Infections: A Phase 2 Randomized Clinical Trial

Thorsten Lehr, PhD; Peter Meiser, PhD; Dominik Selzer, PhD; et al.

Earn CME credit

Podcast: Azelastine Nasal Spray for Prevention of SARS-CoV-2 Infections

Women's Health

Elinzanetant for the Treatment of Vasomotor Symptoms Associated With Menopause: A Phase 3 Randomized Clinical Trial

Nick Panay, MBBS, BSc; Hadine Joffe, MD, MSc; Pauline M. Maki, PhD; et al.

Podcast: Menopause-Associated Vasomotor Symptom Treatment With Elinzanetant

Women's Health

Menopausal Hormone Therapy and Cardiovascular Diseases in Women With Vasomotor Symptoms: A Secondary Analysis of the Women’s Health Initiative Randomized Clinical Trials

Jacques E. Rossouw, MD; Aaron K. Aragaki, MS; JoAnn E. Manson, MD, DrPH; et al.

Editor's Note: Hormone Therapy for Menopausal Vasomotor Symptoms—Better Understanding Cardiovascular Risk; Deborah Grady, MD, MPH; Sharon K. Inouye, MD, MPH; Eve Rittenberg, MD

Aging and Health

Mobile Integrated Health vs a Transitions of Care Coordinator for Patients Discharged After Heart Failure: The Mighty-Heart Randomized Clinical Trial

Ruth Masterson Creber, PhD, MSc, RN; Brock Daniels, MD; Meghan Reading Turchioe, PhD; et al.

Editor's Note: Still Searching for the Right Intervention to Improve Transitions of Care for Patients With Heart Failure; Timothy S. Anderson, MD, MAS; Deborah Grady, MD, MPH

Cognitive Behavioral Therapy for Insomnia in People With Chronic Disease: A Systematic Review and Meta-Analysis

Amelia J. Scott, PhD; Ashleigh B. Correa, BPsych(Hons); Madelyne A. Bisby, PhD; et al.

Aging and Health

Extended Hospital Stays in Medicare Advantage and Traditional Medicare

Brian E. McGarry, PT, PhD; Andrew D. Wilcock, PhD; Ashvin D. Gandhi, PhD; et al.

Invited Commentary

A Novel Approach for Preventing Respiratory Virus Infections

Samuel J. Vidal, MD, PhD; Dan H. Barouch, MD, PhD

Women's Health

The Growing Promise of Elinzanetant for Treatment of Menopausal Symptoms—Sustained Relief Without Hormones

Jaya M. Mehta, MD; Denise M. Millstine, MD; JoAnn E. Manson, MD, DrPH

Editor's Note

Women's Health

Hormone Therapy for Menopausal Vasomotor Symptoms—Better Understanding Cardiovascular Risk

Deborah Grady, MD, MPH; Sharon K. Inouye, MD, MPH; Eve Rittenberg, MD

Women's Health

Still Searching for the Right Intervention to Improve Transitions of Care for Patients With Heart Failure

Timothy S. Anderson, MD, MAS; Deborah Grady, MD, MPH

Less Is More

Overdiagnosis of Cancer—Not Only Associated With Aging

Ilana B. Richman, MD, MHS; Cary P. Gross, MD

Special Communication

Less Is More

The Rise in Early-Onset Cancer in the US Population—More Apparent Than Real

Vishal R. Patel, MD, MPH; Adewole S. Adamson, MD, MPP; H. Gilbert Welch, MD, MPH

Earn CME credit

Editor's Note: Overdiagnosis of Cancer—Not Only Associated With Aging; Ilana B. Richman, MD, MHS; Cary P. Gross, MD

Review

Health Equity

Targeting MASLD and MASH in the US Hispanic/Latino Population: A Review

Nicholas A. Cumpian, MD; Julio A. Gutierrez, MD; William Wu, BS; et al.

Earn CME credit

Podcast: Targeting MASLD and MASH in the US Hispanic/Latino Population

Teachable Moment

Evaluation of Hypercortisolism in Mild Autonomous Cortisol Secretion

Sualeha Khalid, MD; Joseph Theressa N. Parimi, MD, MS; Rozalina G. McCoy, MD, MS

Earn CME credit

Research Letter

Over-the-Counter Retail Naloxone Sales

Bradley D. Stein, MD, PhD; Rachel K. Landis, PhD; Rosanna Smart, PhD; et al.

Challenges in Clinical Electrocardiography

Decoding South African Flag Sign—When Lead V2 Speaks Volumes

Idris F. Ali Amghaiab, MD, MSc; Mansour Khaddr, MD; Fathi I. Ali, MD

Earn CME credit

A Mysterious ST Elevation

Yi-Shuo Liu, BS; Samuel Chin Wei Tan, BS; Yun-Tao Zhao, MD

Earn CME credit

Audio

Azelastine Nasal Spray for Prevention of SARS-CoV-2 Infections

Menopause-Associated Vasomotor Symptom Treatment With Elinzanetant

Targeting MASLD and MASH in the US Hispanic/Latino Population

Comment & Response

Balancing Person-Centered Care and Clinical Evidence in Supplemental Oxygen

Kevin I. Duan, MD, MS; David H. Au, MD, MS

Balancing Person-Centered Care and Clinical Evidence in Supplemental Oxygen—Reply

Angela O. Suen, MD; Susan S. Jacobs, MS, RN; Anand S. Iyer, MD, MSPH

AI and Clinical Care

Caution in Interpreting Results of CT-Cancer Association Study

Chris Hsu, BS; Alexander J. David, BA; James T. Roberts, MD

Editor's Note: Balancing Computed Tomography’s Benefits With Radiation Risks; Ilana B. Richman, MD, MHS; Mitchell H. Katz, MD

Caution in Interpreting Results of CT-Cancer Association Study

Dimitri Alex Dimitroyannis, PhD, MBA; Edward Calabrese, PhD, MA

Caution in Interpreting Results of CT-Cancer Association Study—Reply

Rebecca Smith-Bindman, MD; Amy Berrington de Gonzalez, DPhil; Diana L. Miglioretti, PhD

National Survey of Children’s Health Is Representative of Children, Not Mothers or Other Caregivers

Lydie A. Lebrun-Harris, PhD, MPH; Ashley H. Hirai, PhD; Olivia R. Sappenfield, PhD, MPH

National Survey of Children’s Health Is Representative of Children, Not Mothers or Other Caregivers—Reply

Colleen L. MacCallum-Bridges, PhD; Lindsay K. Admon, MD, MSc; Jamie R. Daw, PhD

Patients as Teachers in Weight Medicine?

Atara Schulhof, BA; Mill Etienne, MD, MPH

Correction

Error in Figure 1 and Discussion Section

Errors in Figure 1

Error in Visual Abstract

Error in Text and Supplement

JAMA Internal Medicine Masthead

JAMA Internal Medicine


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