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JAMA Internal Medicine New Issue December 2025; Volume 185, Number 1

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New Issue

December 2025; Volume 185, Number 12
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Viewpoint

AI and Clinical Care

How Physicians Can Prepare for Generative AI

Daniel J. Morgan, MD, MS; Adam Rodman, MD, MPH; Katherine E. Goodman, JD, PhD

Editorial: Artificial Intelligence and Clinical Care: JAMA Internal Medicine Call for Papers; Cary P. Gross, MD; Ilana B. Richman, MD, MHS; Nathan M. Stall, MD, PhD; et al

Editorial: Women’s Health and Artificial Intelligence; Eve Rittenberg, MD, MA; Cary P. Gross, MD; Melissa Wong, MD, MHDS; Sharon K. Inouye, MD, MPH

Health Equity

Rights of Immigration Detainees to Acute Medical Care

Lawrence A. Haber, MD; Hans P. Erickson, JD; Peter L. Markowitz, JD

Women's Health

The Swinging Pendulum of Menopausal Hormone Therapy

Rebecca C. Thurston, PhD; Alison J. Huang, MD, MAS

Health Care Policy and Law

Advancing a US Single-Payer Model for Cell and Gene Therapy

Audun Brendbekken, MD; Stacie B. Dusetzina, PhD

Inside Story

Remembering the Way

Danielle Chammas, MD

The View From 18 000 Feet—On Healing and Humanity

Kevin Liu, MD, MPH

Original Investigation

Health Equity

Food Insecurity Interventions to Improve Blood Pressure: The Healthy Food First Factorial Randomized Clinical Trial

Seth A. Berkowitz, MD, MPH; Alice S. Ammerman, DrPH, MPH; Patricia Knoepp, MPH; et al.

Editor's Note: Simple Solutions for Complex Problems; Raegan W. Durant, MD, MPH

Health Equity

Voucher for Healthy Foods and Diabetes Control: A Randomized Clinical Trial

Nav Persaud, MD, MSc; Moizza Zia Ul Haq, MPH; Adelaide Buadu, MSc; et al.

Aging and Health

Slow-Tempo Music and Delirium/Coma-Free Days Among Older Adults Undergoing Mechanical Ventilation: A Randomized Clinical Trial

Babar A. Khan, MD, MS; Sikandar H. Khan, DO, MS; Anthony J. Perkins, MS; et al.

Health Care Policy and Law

State Policies and Facility Practices of IV Hydration Spas in the US

Anishaa Sivakumar, MD; Howard P. Forman, MD, MBA; Isabel Wang, BS; et al.

Effectiveness of Colchicine for the Treatment of Long COVID: A Randomized Clinical Trial

Abhinav Bassi, MPH; Niveditha Devasenapathy, PhD, MBBS, MSc; Shani S. Thankachen, MPH; et al.

Health Equity

Survival Benefits of Deceased Donor Kidney Transplant vs Waitlisting

Lin Zhu, PhD; Armando Teixeira-Pinto, PhD; Ryan Gately, MBBS; et al.

Editorial

AI and Clinical Care

Artificial Intelligence and Clinical Care: JAMA Internal Medicine Call for Papers

Cary P. Gross, MD; Ilana B. Richman, MD, MHS; Nathan M. Stall, MD, PhD; et al.

Editorial: Women’s Health and Artificial Intelligence; Eve Rittenberg, MD, MA; Cary P. Gross, MD; Melissa Wong, MD, MHDS; Sharon K. Inouye, MD, MPH

AI and Clinical Care

Women’s Health and Artificial Intelligence

Eve Rittenberg, MD, MA; Cary P. Gross, MD; Melissa Wong, MD, MHDS; et al.

Editorial: Artificial Intelligence and Clinical Care: JAMA Internal Medicine Call for Papers; Cary P. Gross, MD; Ilana B. Richman, MD, MHS; Nathan M. Stall, MD, PhD; et al

Invited Commentary

Aging and Health

The Potential of Music as a Nonpharmacologic Intervention for the ICU—Sound Medicine

Farah Acher Kaiksow, MD, MPP; Eduard Eric Vasilevskis, MD, MPH

Evidence, Opinion, and Uncertainty About COVID-19 Vaccines

Robert M. Califf, MD

Editor's Note

Health Equity

Simple Solutions for Complex Problems

Raegan W. Durant, MD, MPH

Moving Beyond BMI to Define Obesity

Ilana B. Richman, MD, MHS; Sharon K. Inouye, MD, MPH

Review

Less Is More

Supporting Shared Decision-Making in Life-Altering Kidney Therapy Decisions for Older Adults: A Review

Fahad Saeed, MD, MSCI; Areeba Jawed, MD; Shena Gazaway, PhD, RN, CHPN; et al.

Earn CME credit

Teachable Moment

A Case for Early High-Dose Thiamine—Moving From Reaction to Prevention

Douglas N. Goldstein, MD; Alan J. Hunter, MD; Patricio A. Riquelme, MD, PhD

Earn CME credit

Less Is More

The Harms of Inappropriate Food-Specific Immunoglobulin E Testing—Less Is More

Sahana Venkatesh, MD; Fred H. Hsieh, MD

Earn CME credit

Research Letter

Clinical Obesity and All-Cause and Cause-Specific Mortality in UK Biobank

Michael J. Stein, PhD; Heinz Freisling, PhD; Michael F. Leitzmann, DrPH

Editor's Note: Moving Beyond BMI to Define Obesity; Ilana B. Richman, MD, MHS; Sharon K. Inouye, MD, MPH

Durability of 2024-2025 COVID-19 Vaccines Against JN.1 Subvariants

Yi Du, PhD; Sai Paritala, PharmD; Yangjianchen Xu, PhD; et al.

Using the PREVENT Equations to Guide Aspirin Use for Primary Prevention of Cardiovascular Disease

Ahmed Sayed, MBBS; Eric D. Peterson, MD, MPH; Amit Khera, MD, MSc; et al.

Health Care Policy and Law

Hospice Cost-Sharing in the Affordable Care Act Marketplace Individual Plans

David M. Anderson, PhD; Farrah Lynn Madanay, PhD; Sarah H. Cross, PhD, MSW, MPH

Clinical Insights

Higher-Valent Pneumococcal Conjugate Vaccines—Perspective for 2026

Liset Olarte, MD, MSc; Daniel M. Musher, MD; Maria C. Rodriguez-Barradas, MD

Earn CME credit

Challenges in Clinical Electrocardiography

A Distinctive Pattern With Coexisting Malignant Arrhythmias

Guangqiang Wang, MS; Na Zhao, MS; Dongxia Zhang, MS

Earn CME credit

JAMA Internal Medicine Patient Page

Women's Health

Dense Breasts Are Common—Here Is What to Know

Hannah S. Milch, MD; Joann G. Elmore, MD, MPH

Comment & Response

Clinical Cues and Quiet Resistance—Bridging Stewardship Design and Human Decisions

Yu-Hsuan Tai, MD; Tieh-Cheng Fu, MD, PhD; Ching-Mao Chang, MD, PhD

Clinical Cues and Quiet Resistance—Bridging Stewardship Design and Human Decisions—Reply

Shruti K. Gohil, MD, MPH; Ken Kleinman, ScD; Susan S. Huang, MD, MPH

Pharmacologic Confounders in Steatotic Liver Disease Outcomes Research

Shio-Shin Jean, MD; Chih-Cheng Lai, MD

Pharmacologic Confounders in Steatotic Liver Disease Outcomes Research—Reply

Pedro Ochoa-Allemant, MD, MSCE; Rebecca A. Hubbard, PhD; Marina Serper, MD, MS

Potential Limitations of Low-Dose Methotrexate in Inflammatory Knee Osteoarthritis

Chia-Hao Hsu, MD; Charles Liao, MD; Nin-Chieh Hsu, MD, PhD

Aging and Health

Potential Limitations of Low-Dose Methotrexate in Inflammatory Knee Osteoarthritis—Reply

Zhaohua Zhu, PhD; David J. Hunter, PhD, MD; Changhai Ding, PhD, MD

Correction

Article Changed to Open Access

JAMA Internal Medicine Masthead

JAMA Internal Medicine


Artificial Intelligence and Clinical Care: JAMA Internal Medicine Call for Papers
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