JAMA + AI Weekly Update June 28, 2025

In this week's JAMA+ AI Conversations, JAMA+ AI Editor in Chief Roy Perlis, MD, MSc, joined Kenneth Kehl, MD, MPH, a medical oncologist and services researcher at DFCI, to discuss the MatchMiner AI tool and what comes next for AI tools like this.

Learn more and listen to the podcast, "Harnessing AI and Genomics in Clinical Trial Enrollment."

Editor’s Picks in this week’s JAMA+ AI:

• A JAMA Network Open study found that an ML-based triage model using physiologic measures and vital sign patterns from patients with traumatic injuries provided accurate predictions of whether they would require prehospital lifesaving interventions, like a blood transfusion or an airway intervention.
• A JAMA Dermatology Original Investigation and Editorial reported on a novel risk stratification system for cutaneous squamous cell carcinoma that was developed using a large language model with retrieval-augmented generation.