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IN THIS ISSUE OF JAMA
Audio Highlights
Audio Editors' Summary: Scopolamine Butylbromide for End-of-Life Death Rattle, Pulmonary Embolism Workups in COPD Exacerbation, Eosinophilic Esophagitis review, and more
ORIGINAL INVESTIGATION
Caring for the Critically Ill Patient
Effect of Prophylactic Subcutaneous Scopolamine Butylbromide on Death Rattle in Patients at the End of Life: The SILENCE Randomized Clinical Trial
Harriëtte J. van Esch, MD; Lia van Zuylen, MD, PhD; Eric C. T. Geijteman, MD, PhD; et al.
Audio Author Interview: Scopolamine Butylbromide for Preventing End-of-Life Death Rattle
Editorial: Preventing Death Rattle With Prophylactic Subcutaneous Scopolamine Butylbromide; Jared R. Lowe, MD; Laura C. Hanson, MD, MPH
Effect of a Pulmonary Embolism Diagnostic Strategy on Clinical Outcomes in Patients Hospitalized for COPD Exacerbation: A Randomized Clinical Trial
David Jiménez, MD, PhD; Alvar Agustí, MD, PhD; Eva Tabernero, MD; et al.
Earn CME credit
Trends in Cardiovascular Risk Factors in US Adults by Race and Ethnicity and Socioeconomic Status, 1999-2018
Jiang He, MD, PhD; Zhengbao Zhu, MD, PhD; Joshua D. Bundy, PhD, MPH; et al.
US Emergency Department Visits Attributed to Medication Harms, 2017-2019
Daniel S. Budnitz, MD, MPH; Nadine Shehab, PharmD, MPH; Maribeth C. Lovegrove, MPH; et al.
RESEARCH LETTER
Mask-Wearing Behavior at the 2021 NCAA Men’s Basketball Tournament
Joshua R. Vest, PhD, MPH; Justin Blackburn, PhD; Shama Cash-Goldwasser, MD, MPH; et al.
Earn CME credit
Physician Practice Interruptions in the Treatment of Medicare Patients During the COVID-19 Pandemic
Hannah T. Neprash, PhD; Michael E. Chernew, PhD
VIEWPOINT
Strengthening Global Health Security and Reforming the International Health Regulations: Making the World Safer From Future Pandemics
Antony J. Blinken, JD; Xavier Becerra, JD
An International Agreement on Pandemic Prevention and Preparedness
Lawrence O. Gostin, JD; Sam F. Halabi, JD, MPhil; Kevin A. Klock, JD
Holding Hope for Patients With Serious Illness
Abby Rosenberg, MD, MS, MA; Robert M Arnold, MD; Yael Schenker, MD, MAS
A PIECE OF MY MIND
Good Enough for Whom?
Sharon Reece, MD
EDITORIAL
Preventing Death Rattle With Prophylactic Subcutaneous Scopolamine Butylbromide
Jared R. Lowe, MD; Laura C. Hanson, MD, MPH
Audio Author Interview: Scopolamine Butylbromide for Preventing End-of-Life Death Rattle
Ninth International Congress on Peer Review and Scientific Publication: Call for Abstracts
John P. A. Ioannidis, MD, DSc; Michael Berkwits, MD, MSCE; Annette Flanagin, RN, MA; et al.
REVIEW
Eosinophilic Esophagitis: A Review
Amanda Muir, MD, MSTR; Gary W. Falk, MD, MS
Earn CME credit
JAMA INSIGHTS
Infectious Keratitis in 2021
Marlene L. Durand, MD; Miriam Baron Barshak, MD; James Chodosh, MD, MPH
JAMA CLINICAL GUIDELINES SYNOPSIS
Inferior Vena Cava Filters for the Treatment of Patients With Venous Thromboembolic Disease
Osman Ahmed, MD; Adam S. Cifu, MD; Jonathan Paul, MD
MEDICAL NEWS & PERSPECTIVES
How COVID-19 Made It Even Tougher to Know ICU Patients as Individuals
Rita Rubin, MA
JAMA Medical News Audio: Rebounding From COVID-19’s Reversal of Recent Progress in the ICU
Quick Uptakes
Choose ARBs Over ACE Inhibitors for First-line Hypertension Treatment, Large New Analysis Suggests
Jennifer Abbasi
NEWS FROM THE JAMA NETWORK
Pediatric Depression and Anxiety Doubled During the Pandemic
Anita Slomski
Cycling May Lower Mortality Risk in People Who Have Diabetes
Anita Slomski
Oral Upadacitinib Beats Subcutaneous Dupilumab for Atopic Dermatitis
Anita Slomski
Study Projects Lifetime Benefits of Dapagliflozin in HFrEF
Anita Slomski
NEWS FROM THE FOOD AND DRUG ADMINISTRATION
Mandated Education for Opioid Prescribers Is Up for Discussion
Rebecca Voelker, MSJ
A First in Stroke Rehabilitation
Rebecca Voelker, MS
FDA Reaches a Milestone in Generic Drug Approvals
Rebecca Voelker, MSJ
THE ARTS AND MEDICINE
Japanese Medical Mnemonics—Language, Reflection, and Art
Nick Love, MD, PhD; Yuichi J. Shimada, MD, MPH
POETRY AND MEDICINE
Every Time
Alex Ruuska, BA, BS
JAMA REVISITED
Modern Problems in Two Medical Specialties
JAMA PATIENT PAGE
Intermittent Fasting
Zhaoping Li, MD, PhD; David Heber, MD, PhD
AUDIO
Audio Editors' Summary
Scopolamine Butylbromide for End-of-Life Death Rattle, Pulmonary Embolism Workups in COPD Exacerbation, Eosinophilic Esophagitis review, and more
Audio Author Interview
Scopolamine Butylbromide for Preventing End-of-Life Death Rattle
JAMA Medical News Audio
Rebounding From COVID-19’s Reversal of Recent Progress in the ICU
COMMENT & RESPONSE
US Preventive Services Task Force Recommendation Statement on Screening for Colorectal Cancer
Shida Haghighat, MD, MPH; Daniel A. Sussman, MD, MSPH; Amar Deshpande, MD
Audio Clinical Review: USPSTF Recommendation: Screening for Colorectal Cancer
US Preventive Services Task Force Recommendation Statement on Screening for Colorectal Cancer—Reply
Michael J. Barry, MD; Karina Davidson, PhD, MASc; Carol M. Mangione, MD, MSPH
Continuous Glucose Monitoring and Glycemic Control in Patients With Type 2 Diabetes Treated With Basal Insulin
Kevin Cowart, PharmD, MPH; Nicholas W. Carris, PharmD
Continuous Glucose Monitoring and Glycemic Control in Patients With Type 2 Diabetes Treated With Basal Insulin
Wellbert Hernández-Núñez, MD; Jesús Zacarías Villareal-Pérez, MD; René Rodríguez-Gutiérrez, MD, MSc, PhD
Continuous Glucose Monitoring and Glycemic Control in Patients With Type 2 Diabetes Treated With Basal Insulin—Reply
Thomas W. Martens, MD; Roy W. Beck, MD, PhD; Richard M. Bergenstal, MD
CORRECTION
Incorrect Value in Table
Error in Figure
Transposed Column Heads in Table
JAMA MASTHEAD
JAMA
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