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IN THIS ISSUE OF JAMA
Audio Highlights
Audio Editors' Summary: Volume Replacement in Cardiac Surgery, Omecamtiv Mecarbil for Heart Failure With Reduced Ejection Fraction, Diagnosis and Management of Hyponatremia, and more
ORIGINAL INVESTIGATION
Effect of 4% Albumin Solution vs Ringer Acetate on Major Adverse Events in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass: A Randomized Clinical Trial
Eero Pesonen, MD, PhD; Hanna Vlasov, MD; Raili Suojaranta, MD, PhD; et al.
Editorial: Albumin vs Crystalloid Fluid for Resuscitation in Cardiac Surgery: New Evidence and Arguments in the Timeless Debate; Mihai V. Podgoreanu, MD; Negmeldeen Mamoun, MD, PhD
Effect of Omecamtiv Mecarbil on Exercise Capacity in Chronic Heart Failure With Reduced Ejection Fraction: The METEORIC-HF Randomized Clinical Trial
Gregory D. Lewis, MD; Adriaan A. Voors, MD, PhD; Alain Cohen-Solal, MD, PhD; et al.
Audio Author Interview: Can Omecamtiv Mecarbil Improve Peak Exercise Capacity in Patients With Heart Failure With Reduced Ejection Fraction (HFrEF)?
Editorial: Omecamtiv Mecarbil as a Therapy for Heart Failure With Low Ejection Fraction; Mark H. Drazner, MD, MSc
Effect of Fluid Bolus Administration on Cardiovascular Collapse Among Critically Ill Patients Undergoing Tracheal Intubation: A Randomized Clinical Trial
Derek W. Russell, MD; Jonathan D. Casey, MD, MSc; Kevin W. Gibbs, MD; et al.
RESEARCH LETTER
Association of Omicron vs Wild-type SARS-CoV-2 Variants With Hospital-Onset SARS-CoV-2 Infections in a US Regional Hospital System
Michael Klompas, MD, MPH; Michael C. Pandolfi, BS; Ansa B. Nisar, BS; et al.
Updated US Infection- and Vaccine-Induced SARS-CoV-2 Seroprevalence Estimates Based on Blood Donations, July 2020-December 2021
Jefferson M. Jones, MD, MPH; Jean D. Opsomer, PhD, MBA; Mars Stone, PhD; et al.
Earn CME credit
VIEWPOINT
Increases in Disparities in US Drug Overdose Deaths by Race and Ethnicity: Opportunities for Clinicians and Health Systems
Mbabazi Kariisa, PhD, MPH; Puja Seth, PhD; Christopher M. Jones, PharmD, DrPH
A National Tracking System for Nonfatal Drug Overdoses
Rahul Gupta, MD, MPH, MBA; David R. Holtgrave, PhD
The Federal Global Migration and Quarantine Network: A Report From the National Academies of Sciences, Engineering, and Medicine
Lawrence O. Gostin, JD; Georges C. Benjamin, MD; Tequam Worku, MPH
Promoting the Values for Surrogate Decision-making
David Wendler, PhD
A PIECE OF MY MIND
Spinning
Margaret Ryan, MD, MPH
EDITORIAL
Albumin vs Crystalloid Fluid for Resuscitation in Cardiac Surgery: New Evidence and Arguments in the Timeless Debate
Mihai V. Podgoreanu, MD; Negmeldeen Mamoun, MD, PhD
Omecamtiv Mecarbil as a Therapy for Heart Failure With Low Ejection Fraction
Mark H. Drazner, MD, MSc
Audio Author Interview: Can Omecamtiv Mecarbil Improve Peak Exercise Capacity in Patients With Heart Failure With Reduced Ejection Fraction (HFrEF)?
REVIEW
Diagnosis and Management of Hyponatremia: A Review
Horacio J. Adrogué, MD; Bryan M. Tucker, DO, MS; Nicolaos E. Madias, MD
Earn CME credit
JAMA INSIGHTS
Women's Health
Breast Masses in Biological Females
Monique Swain, MD; Myrlene Jeudy, MD
Earn CME credit
JAMA CLINICAL GUIDELINES SYNOPSIS
Evaluation and Diagnosis of Chest Pain
David G. Beiser, MD, MS; Adam S. Cifu, MD; Jonathan Paul, MD
Earn CME credit
MEDICAL NEWS & PERSPECTIVES
Global Monkeypox Outbreaks Spur Drug Research for the Neglected Disease
Emily Harris
Audio Author Interview: Diagnosis, Prevention, and Treatment of Monkeypox
NEWS FROM THE FOOD AND DRUG ADMINISTRATION
First Systemic Treatment for Severe Alopecia Is Approved
Rita Rubin, MA
Campaign Against e-Cigarette Use Targets “Next Legends”
Rita Rubin, MA
New Education Initiative on Dietary Supplements
Rita Rubin, MA
GLOBAL HEALTH
As Unexplained Hepatitis Spreads, WHO Urges Action
Howard D. Larkin
Mix-and-Match COVID-19 Boosters After Inactivated Virus Vaccine
Howard D. Larkin
Updated Malaria Recommendations for Children and Pregnant People
Howard D. Larkin
POETRY AND MEDICINE
Postoperative Day One
Ivana Viani, MD
JAMA REVISITED
Smallpox
JAMA PATIENT PAGE
Lumbar Spinal Stenosis
Kristin L. Walter, MD, MS; John E. O’Toole, MD, MS
AUDIO
Audio Editors' Summary
Volume Replacement in Cardiac Surgery, Omecamtiv Mecarbil for Heart Failure With Reduced Ejection Fraction, Diagnosis and Management of Hyponatremia, and more
Audio Author Interview
Can Omecamtiv Mecarbil Improve Peak Exercise Capacity in Patients With Heart Failure With Reduced Ejection Fraction (HFrEF)?
Audio Author Interview
Diagnosis, Prevention, and Treatment of Monkeypox
COMMENT & RESPONSE
COVID-19 ARDS and Posttraumatic Stress Disorder in Family Members After ICU Discharge
Hung-Yi Lin, MD; Mu-Hong Chen, MD; Chih-Sung Liang, MD
COVID-19 ARDS and Posttraumatic Stress Disorder in Family Members After ICU Discharge
Eli Weber, PhD; Nicole Van Buren, MD; Thomas Cunningham, PhD
COVID-19 ARDS and Posttraumatic Stress Disorder in Family Members After ICU Discharge—Reply
Elie Azoulay, MD, PhD; Frédéric Pochard, MD, PhD; Nancy Kentish-Barnes, PhD
Remote Patient Monitoring During COVID-19
Jordan Kenik, MD, MPH
Remote Patient Monitoring During COVID-19—Reply
Peter J. Pronovost, MD, PhD; Melissa D. Cole, APRN; Robert M. Hughes, DO
Echocardiographic Measures of Left Atrial Function and Size and Incident Dementia
Gianluca Rigatelli, MD, PhD; Marco Zuin, MD
Echocardiographic Measures of Left Atrial Function and Size and Incident Dementia
Yu-Syuan Chen, MD; Yen-Po Lin, MD
Echocardiographic Measures of Left Atrial Function and Size and Incident Dementia—Reply
Wendy Wang, MPH; Scott D. Solomon, MD; Lin Yee Chen, MD
JAMA MASTHEAD
JAMA
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