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IN THIS ISSUE OF JAMA
Audio Highlights
Audio Editors' Summary: Thrombolysis Before Thrombectomy for Stroke, USPSTF Guideline on Smoking Cessation, US Health Policy Theme Issue, and more
ORIGINAL INVESTIGATION
Effect of Endovascular Treatment Alone vs Intravenous Alteplase Plus Endovascular Treatment on Functional Independence in Patients With Acute Ischemic Stroke: The DEVT Randomized Clinical Trial
Wenjie Zi, MD; Zhongming Qiu, MD; Fengli Li, MD; et al.
Earn CME credit
Conversations with Dr Bauchner: Thrombolysis Before Thrombectomy for Stroke
Editorial: Intravenous Thrombolysis Before Endovascular Thrombectomy for Acute Ischemic Stroke; Jeffrey L. Saver, MD; Opeolu Adeoye, MD, MS
Video: Thrombolysis Before Thrombectomy for Stroke
Effect of Mechanical Thrombectomy Without vs With Intravenous Thrombolysis on Functional Outcome Among Patients With Acute Ischemic Stroke: The SKIP Randomized Clinical Trial
Kentaro Suzuki, MD, PhD; Yuji Matsumaru, MD, PhD; Masataka Takeuchi, MD; et al.
Earn CME credit
Conversations with Dr Bauchner: Thrombolysis Before Thrombectomy for Stroke
Editorial: Intravenous Thrombolysis Before Endovascular Thrombectomy for Acute Ischemic Stroke; Jeffrey L. Saver, MD; Opeolu Adeoye, MD, MS
Video: Thrombolysis Before Thrombectomy for Stroke
Effect of Discontinuing vs Continuing Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers on Days Alive and Out of the Hospital in Patients Admitted With COVID-19: A Randomized Clinical Trial
Renato D. Lopes, MD, PhD; Ariane V. S. Macedo, MD, MSc; Pedro G. M. de Barros E Silva, MD, PhD; et al.
RESEARCH LETTER
Readmission and Death After Initial Hospital Discharge Among Patients With COVID-19 in a Large Multihospital System
John P. Donnelly, PhD; Xiao Qing Wang, MPH; Theodore J. Iwashyna, MD, PhD; et al.
Earn CME credit
US PREVENTIVE SERVICES TASK FORCE
Recommendation Statement
Interventions for Tobacco Smoking Cessation in Adults, Including Pregnant Persons: US Preventive Services Task Force Recommendation Statement
US Preventive Services Task Force
Earn CME credit
Conversations with Dr Bauchner: USPSTF Recommendation: Tobacco Cessation in Adults
JAMA Clinical Guidelines Synopsis: Initiating Pharmacologic Treatment in Tobacco-Dependent Adults; Atul Jain, MD, MS; Andrew M. Davis, MD, MPH
Editorial: A Comprehensive Approach to Increase Adult Tobacco Cessation; Brenna VanFrank, MD, MSPH; Letitia Presley-Cantrell, PhD
JAMA Patient Page : Interventions to Promote Tobacco Cessation ; Jill Jin, MD, MPH
Evidence Report
Interventions for Tobacco Cessation in Adults, Including Pregnant Persons: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force
Carrie D. Patnode, PhD, MPH; Jillian T. Henderson, PhD, MPH; Erin L. Coppola, MPH; et al.
VIEWPOINT
Health Policy
The Language of Health Care Reform
Larry Levitt, MPP
Health Policy
Executive Action to Expand Health Services in the Biden Administration
Timothy M. Westmoreland, JD; M. Gregg Bloche, MD, JD; Lawrence O. Gostin, JD
The Ethics of Continuing Placebo in SARS-CoV-2 Vaccine Trials
Annette Rid, MD; Marc Lipsitch, DPhil; Franklin G. Miller, PhD
Earn CME credit
Conversations with Dr Bauchner: Coronavirus Vaccine FDA Update
Evaluating SARS-CoV-2 Vaccines After Emergency Use Authorization or Licensing of Initial Candidate Vaccines
Steven Joffe, MD, MPH
Earn CME credit
Conversations with Dr Bauchner: Coronavirus Vaccine FDA Update
Public Health Messaging in an Era of Social Media
Raina M. Merchant, MD, MSHP; Eugenia C. South, MD, MSHP; Nicole Lurie, MD, MSPH
Earn CME credit
Conversations with Dr Bauchner: Public Health Messaging in an Era of Social Media
A PIECE OF MY MIND
Root Cause Analysis
Megan Paulsen, MD
EDITORIAL
Health Policy
Health Care Is a Right, Not a Privilege: A New Series on US Health Care and Health Policy
Howard Bauchner, MD; Phil B. Fontanarosa, MD, MBA; Karen Joynt Maddox, MD, MPH
Intravenous Thrombolysis Before Endovascular Thrombectomy for Acute Ischemic Stroke
Jeffrey L. Saver, MD; Opeolu Adeoye, MD, MS
Conversations with Dr Bauchner: Thrombolysis Before Thrombectomy for Stroke
Video: Thrombolysis Before Thrombectomy for Stroke
A Comprehensive Approach to Increase Adult Tobacco Cessation
Brenna VanFrank, MD, MSPH; Letitia Presley-Cantrell, PhD
Conversations with Dr Bauchner: USPSTF Recommendation: Tobacco Cessation in Adults
JAMA PERFORMANCE IMPROVEMENT
Safe Central Venous Access in an Overburdened Health System
Karen Woo, MD, MS; David Rigberg, MD; Peter F. Lawrence, MD
Video: Ultrasound-Guided Popliteal Vein Access in Prone Patients
JAMA CLINICAL GUIDELINES SYNOPSIS
Initiating Pharmacologic Treatment in Tobacco-Dependent Adults
Atul Jain, MD, MS; Andrew M. Davis, MD, MPH
Audio Clinical Review: Pharmacologic Management of Tobacco Cessation
MEDICAL NEWS & PERSPECTIVES
COVID-19 Conspiracies and Beyond: How Physicians Can Deal With Patients’ Misinformation
Jennifer Abbasi
Earn CME credit
JAMA Medical News Audio: COVID-19 Conspiracies and Beyond: How Physicians Can Deal With Patients’ Misinformation
Quick Uptakes
New Guidance for Type 1 Diabetes Continuous Glucose Monitoring Use During Exercise
Mary Chris Jaklevic, MSJ
NEWS FROM THE FOOD AND DRUG ADMINISTRATION
First Drug Approved for Rare Genetic Disorder Affecting Kidneys
Mary Chris Jaklevic, MSJ
Avoid Masks With Metal During Magnetic Resonance Imaging
Mary Chris Jaklevic, MSJ
Imaging Drug for Prostate Cancer
Mary Chris Jaklevic, MSJ
GLOBAL HEALTH
WHO Launches Global Push to Eliminate Cervical Cancer
Bridget M. Kuehn, MSJ
Monthly Malaria Prophylaxis Cuts Child Deaths in Sub-Saharan Africa
Bridget M. Kuehn, MSJ
Drop in Vaccination Causes Surge in Global Measles Cases, Deaths
Bridget M. Kuehn, MSJ
POETRY AND MEDICINE
Spraying Cotton in Bolivar County, Mississippi, the Summer Following My First Year of Medical School
Doug Hester, MD
JAMA REVISITED
The Cause of Cancer
JAMA PATIENT PAGE
Interventions to Promote Tobacco Cessation
Jill Jin, MD, MPH
Conversations with Dr Bauchner: USPSTF Recommendation: Tobacco Cessation in Adults
AUDIO
Audio Editors' Summary
Thrombolysis Before Thrombectomy for Stroke, USPSTF Guideline on Smoking Cessation, US Health Policy Theme Issue, and more
Conversations with Dr Bauchner
Thrombolysis Before Thrombectomy for Stroke
Conversations with Dr Bauchner
USPSTF Recommendation: Tobacco Cessation in Adults
Audio Clinical Review
Pharmacologic Management of Tobacco Cessation
Conversations with Dr Bauchner
Public Health Messaging in an Era of Social Media
JAMA Medical News Audio
COVID-19 Conspiracies and Beyond: How Physicians Can Deal With Patients’ Misinformation
VIDEO
Thrombolysis Before Thrombectomy for Stroke
Jeffrey L. Saver, MD, director of UCLA’s Comprehensive Stroke and Vascular Neurology Program and a JAMA Associate Editor, discusses 2 randomized trials comparing outcomes for stroke patients treated with IVT prior to EVT vs EVT alone.
Ultrasound-Guided Popliteal Vein Access in Prone Patients
This procedure video demonstrates a simple ultrasound-guided technique for obtaining large-bore IV access through the popliteal vein.
COMMENT & RESPONSE
Effect of Tidal Volume on Pulmonary Outcomes After Surgery
Chunmei Zhao, MD; Yuesong Pan, PhD; Fang Luo, MD
Effect of Tidal Volume on Pulmonary Outcomes After Surgery
Maximilian S. Schaefer, MD; Daniel Talmor, MD; Elias N. Baedorf-Kassis, MD
Effect of Tidal Volume on Pulmonary Outcomes After Surgery
Varun Suresh, MD, DM
Effect of Tidal Volume on Pulmonary Outcomes After Surgery—Reply
Dharshi Karalapillai, MD; Ary Serpa Neto, MD, PhD; Rinaldo Bellomo, MD
Physician Performance in the Medicare Merit-based Incentive Payment System
Vinay K. Rathi, MD, MBA
Physician Performance in the Medicare Merit-based Incentive Payment System—Reply
Kenton J. Johnston, PhD; Jason M. Hockenberry, PhD; Karen E. Joynt Maddox, MD, MPH
CORRECTION
Table Inversion Error
JAMA MASTHEAD
JAMA
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