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IN THIS ISSUE OF JAMA
Audio Highlights
Audio: Regular Use of Morphine for Chronic Breathlessness in COPD, Treatment Time and In-Hospital Mortality With STEMI, Change in Travel Time to US Abortion Facilities After Dobbs Decision, and more
ORIGINAL INVESTIGATION
Effect of Regular, Low-Dose, Extended-release Morphine on Chronic Breathlessness in Chronic Obstructive Pulmonary Disease: The BEAMS Randomized Clinical Trial
Magnus Ekström, MD, PhD; Diana Ferreira, MD, PhD; Sungwon Chang, PhD; et al.
Editorial: Dyspnea—When a Sensation Becomes a Symptom; Richard M. Schwartzstein, MD
Treatment Time and In-Hospital Mortality Among Patients With ST-Segment Elevation Myocardial Infarction, 2018-2021
James G. Jollis, MD; Christopher B. Granger, MD; Jessica K. Zègre-Hemsey, RN, PhD; et al.
Editorial: Time to Treatment in ST-Segment Elevation Myocardial Infarction: Identifying Dangerous Delays or Diminishing Returns? ; Andrew S. Oseran, MD, MBA; Robert W. Yeh, MD, MSc
Audio: Highlights From the American Heart Association’s Scientific Sessions 2022
Estimated Travel Time and Spatial Access to Abortion Facilities in the US Before and After the Dobbs v Jackson Women’s Health Decision
Benjamin Rader, MPH; Ushma D. Upadhyay, PhD, MPH; Neil K. R. Sehgal, BA; et al.
Editorial: The A Word—Our Collective Scarlet Letter; Melissa A. Simon, MD, MPH
Association of Texas’ 2021 Ban on Abortion in Early Pregnancy With the Number of Facility-Based Abortions in Texas and Surrounding States
Kari White, PhD, MPH; Gracia Sierra, PhD, MS; Klaira Lerma, MPH; et al.
Editorial: The A Word—Our Collective Scarlet Letter; Melissa A. Simon, MD, MPH
RESEARCH LETTER
Reported Awareness and Adoption of 2021 Estimated Glomerular Filtration Rate Equations Among US Clinical Laboratories, March 2022
Jonathan R. Genzen, MD, PhD; Rhona J. Souers, MS; Lauren N. Pearson, DO, MPH; et al.
Extended Follow-up of Microbiome Therapeutic SER-109 Through 24 Weeks for Recurrent Clostridioides difficile Infection in a Randomized Clinical Trial
Stuart H. Cohen, MD; Thomas J. Louie, MD; Matthew Sims, MD, PhD; et al.
Human Monkeypox Virus Infection in the Immediate Period After Receiving Modified Vaccinia Ankara Vaccine
Aniruddha Hazra, MD; Laura Rusie, ScM; Trevor Hedberg, MPH, PA-C; et al.
VIEWPOINT
Closing the Loophole on Hemp-Derived Cannabis Products: A Public Health Priority
Alyssa F. Harlow, PhD, MPH; Adam M. Leventhal, PhD; Jessica L. Barrington-Trimis, PhD
The Tobacco Industry and Harm Reduction
Howard K. Koh, MD, MPH; Michael C. Fiore, MD, MPH, MBA
Implications of Dobbs for the (Re)Criminalization of Intimacy Among LGBTQ Individuals
Joanne D. Rosen, JD, MA; Chris Beyrer, MD, MPH
A PIECE OF MY MIND
Role Reversal
Julia Brekke-Riedl, PhD
EDITORIAL
Dyspnea—When a Sensation Becomes a Symptom
Richard M. Schwartzstein, MD
Time to Treatment in ST-Segment Elevation Myocardial Infarction: Identifying Dangerous Delays or Diminishing Returns?
Andrew S. Oseran, MD, MBA; Robert W. Yeh, MD, MSc
The International Code of Medical Ethics of the World Medical Association
Ramin Walter Parsa-Parsi, MD, MPH
JAMA CLINICAL GUIDELINES SYNOPSIS
Diagnosis and Treatment of Infertility in Men
Joshua A. Halpern, ME, MS; Andrew M. Davis, MD, MPH; Robert E. Brannigan, MD
Earn CME credit
JAMA CLINICAL CHALLENGE
Intermittent Chest Pain in a 46-Year-Old Patient
Carlos Plappert, MD; Mohammad Sherif, MD; Christian Oeing, MD
Earn CME credit
MEDICAL NEWS & PERSPECTIVES
After the First Pig-to-Human Heart Transplant, Scientists Look to the Future of Cardiac Xenotransplantation
Jyoti Madhusoodanan
Audio: Highlights From the American Heart Association’s Scientific Sessions 2022
NEWS FROM THE CENTERS FOR DISEASE CONTROL AND PREVENTION
CDC Report: Urgent Need to Address Teens’ Adverse Experiences During Pandemic
Bridget M. Kuehn, MSJ
Targeted Flu Vaccination Campaigns Needed for Certain Racial and Ethnic Groups
Bridget M. Kuehn, MSJ
CLINICAL TRIALS UPDATE
Financial Vouchers Led to Higher Smoking Abstinence During Pregnancy
Anita Slomski
Intranasal COVID-19 Vaccine Disappointing in First-in-Human Trial
Anita Slomski
Colonoscopy Did Not Reduce Cancer Deaths in Trial
Anita Slomski
Shorter Duration of Antibiotics Noninferior for Lyme Disease
Anita Slomski
HEALTH AGENCIES UPDATE
White House Fixes “Family Glitch” in Health Insurance Subsidies
Melissa Suran, PhD, MSJ
New Guidance for Reducing Health Care Organizations’ Carbon Emissions
Melissa Suran, PhD, MSJ
GAO Calls for Nationwide Analysis of “Forever Chemicals”
Melissa Suran, PhD, MSJ
POETRY AND MEDICINE
Omicron, 621 Days Out
Stacy Nigliazzo, MSN, RN
JAMA REVISITED
Development of Bacterial Resistance to Antibiotics
JAMA PATIENT PAGE
What Is Multiple Sclerosis?
Revital Marcus, MD
JAMA Patient Page Audio Version: What Is Multiple Sclerosis?
AUDIO
Editor's Summary Audio
Regular Use of Morphine for Chronic Breathlessness in COPD, Treatment Time and In-Hospital Mortality With STEMI, Change in Travel Time to US Abortion Facilities After Dobbs Decision, and more
Medical News Audio
Highlights From the American Heart Association’s Scientific Sessions 2022
JAMA Patient Page Audio Version
What Is Multiple Sclerosis?
COMMENT & RESPONSE
Use of Albumin Solution in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass
Yongqi Zhou, MD; Tao Zhu, MD, PhD; Chan Chen, MD, PhD
Use of Albumin Solution in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass—Reply
Eero Pesonen, MD, PhD; Tatu Juvonen, MD, PhD; Ville Pettilä, MD, PhD
US Tracking System for Nonfatal Drug Overdoses
Steven M. Marcus, MD
US Tracking System for Nonfatal Drug Overdoses—Reply
Rahul Gupta, MD, MPH, MBA; David R. Holtgrave, PhD
Fluid Bolus Administration and Cardiovascular Collapse in Critically Ill Patients Undergoing Tracheal Intubation
Ambika Tejpal, MD; Matteo Parotto, MD, PhD; Michael C. Sklar, MD
Fluid Bolus Administration and Cardiovascular Collapse in Critically Ill Patients Undergoing Tracheal Intubation
Ward H. van der Ven, MD; Alexander P. J. Vlaar, MD, PhD, MBA; Denise P. Veelo, MD, PhD
Fluid Bolus Administration and Cardiovascular Collapse in Critically Ill Patients Undergoing Tracheal Intubation
Nirvik Pal, MD; Miklos D. Kertai, MD, PhD; John Butterworth, MD
Fluid Bolus Administration and Cardiovascular Collapse in Critically Ill Patients Undergoing Tracheal Intubation—Reply
Derek W. Russell, MD; Jonathan D. Casey, MD, MSc; Matthew W. Semler, MD, MSc
JAMA MASTHEAD
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