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IN THIS ISSUE OF JAMA
Audio Highlights
Audio: Prophylactic Antibiotics in Severe Alcohol-Related Hepatitis, Autotaxin Inhibitor Ziritaxestat for Idiopathic Pulmonary Fibrosis, Review of Cirrhosis, and more
ORIGINAL INVESTIGATION
Effect of Prophylactic Antibiotics on Mortality in Severe Alcohol-Related Hepatitis: A Randomized Clinical Trial
Alexandre Louvet, MD; Julien Labreuche, MSc; Thong Dao, MD; et al.
Editorial: The Role of Prophylactic Antibiotics for Patients With Severe Alcohol-Related Hepatitis; Ewan Forrest, MD; William Bernal, MD
Ziritaxestat, a Novel Autotaxin Inhibitor, and Lung Function in Idiopathic Pulmonary Fibrosis: The ISABELA 1 and 2 Randomized Clinical Trials
Toby M. Maher, MD, PhD; Paul Ford, MD, PhD; Kevin K. Brown, MD; et al.
Editorial: The Future of Clinical Trials in Idiopathic Pulmonary Fibrosis; Anna J. Podolanczuk, MD, MS; Luca Richeldi, MD, PhD; Fernando J. Martinez, MD, MS
Piperacillin-Tazobactam Compared With Cefoxitin as Antimicrobial Prophylaxis for Pancreatoduodenectomy: A Randomized Clinical Trial
Michael I. D’Angelica, MD; Ryan J. Ellis, MD, MSc; Jason B. Liu, MD, MSc; et al.
Editorial: Informing a Rational Approach to Antimicrobial Prophylaxis in Open Pancreatoduodenectomy; Anthony Charles, MD, MPH; Preeti N. Malani, MD, MSJ
RESEARCH LETTER
Trends in Deaths From Falls Among Adults Aged 65 Years or Older in the US, 1999-2020
Alexis R. Santos-Lozada, PhD
Five-Year Sales for Newly Marketed Prescription Drugs With and Without Initial Orphan Drug Act Designation
S. Sean Tu, JD, PhD; Sarosh Nagar; Aaron S. Kesselheim, MD, JD, MPH; et al.
VIEWPOINT
A Policy Framework for the Growing Influence of Private Equity in Health Care Delivery
Christopher Cai, MD; Zirui Song, MD, PhD
Hospital Consolidation: The Rise of Geographically Distant Mergers
Amol S. Navathe, MD, PhD; John E. Connolly, BA
The Supreme Court Is Harming Public Health and the Environment
Lawrence O. Gostin, JD; Sarah Wetter, JD, MPH
A PIECE OF MY MIND
The Stories We Don’t Know
Joana E. Andoh, MD
EDITORIAL
The Role of Prophylactic Antibiotics for Patients With Severe Alcohol-Related Hepatitis
Ewan Forrest, MD; William Bernal, MD
The Future of Clinical Trials in Idiopathic Pulmonary Fibrosis
Anna J. Podolanczuk, MD, MS; Luca Richeldi, MD, PhD; Fernando J. Martinez, MD, MS
Informing a Rational Approach to Antimicrobial Prophylaxis in Open Pancreatoduodenectomy
Anthony Charles, MD, MPH; Preeti N. Malani, MD, MSJ
REVIEW
Diagnosis and Management of Cirrhosis and Its Complications: A Review
Elliot B. Tapper, MD; Neehar D. Parikh, MD, MS
Earn CME credit
Audio: Management of Cirrhosis in 2023
JAMA CLINICAL CHALLENGE
Abdominal Pain and Hypotension in a 70-Year-Old Woman
Francesco Pata, MD, PhD; Giovanni Stamati, MD; Bruno Nardo, MD, PhD
Earn CME credit
Video: Removal of a Gallstone Obstructing the Middle Ileum of a Woman With Nausea, Vomiting, and Abdominal Pain
EDITOR'S NOTE
“Order in the Gulf Death Imposes”—Poetry and War
Rafael Campo, MA, MD
MEDICAL NEWS & PERSPECTIVES
Quick Uptakes
What a Study of Hibernating Bears Tells Us About Deep Vein Thrombosis
Jennifer Abbasi
Audio: April 2023 Medical News Summary
MEDICAL NEWS IN BRIEF
Study: No More Than 6 Teaspoons of Added Sugar per Day
Emily Harris
Research Shows Air Pollution Promotes Lung Cancer
Emily Harris
Blood Donor Sex Not Tied to Recipient Survival
Emily Harris
Rule Tackles Medicare Advantage Marketing, Prior Authorization
Emily Harris
Gun Violence Affects More Than Half of US Adults
Emily Harris
Nondrug Interventions for Dementia Improved Life, Reduced Costs
Emily Harris
RSV Infection Might Be Resuming Prepandemic Patterns
Emily Harris
How Parents’ Views Are Tied to Children’s COVID-19 Vaccination
Emily Harris
FDA Approves Vilobelimab for Emergency Use in Hospitalized Adults
Emily Harris
POETRY AND MEDICINE
Rocket Strike on a Market
Frederick Foote, MD
Editor's Note: “Order in the Gulf Death Imposes”—Poetry and War; Rafael Campo, MA, MD
JAMA REVISITED
Foreign Letters: London
JAMA PATIENT PAGE
What Is Marfan Syndrome?
Heidi M. Connolly, MD; Talha Niaz, MBBS; Juan M. Bowen, MD
AUDIO
Editor’s Summary Audio
Prophylactic Antibiotics in Severe Alcohol-Related Hepatitis, Autotaxin Inhibitor Ziritaxestat for Idiopathic Pulmonary Fibrosis, Review of Cirrhosis, and more
Clinical Reviews Audio
Management of Cirrhosis in 2023
Medical News Audio
April 2023 Medical News Summary
VIDEO
JAMA Video
Removal of a Gallstone Obstructing the Middle Ileum of a Woman With Nausea, Vomiting, and Abdominal Pain
COMMENT & RESPONSE
Regulatory Submission Characteristics and Recalls of Medical Devices Receiving 510(k) Clearance
Vinay K. Rathi, MD, MBA
Regulatory Submission Characteristics and Recalls of Medical Devices Receiving 510(k) Clearance
Omar Robles, PhD, MBA
Regulatory Submission Characteristics and Recalls of Medical Devices Receiving 510(k) Clearance—Reply
Alexander O. Everhart, PhD; Yi Zhu, MS; Ariel D. Stern, PhD
High-Flow Nasal Oxygen vs Standard Oxygen Therapy and Length of Hospital Stay in Children With Acute Hypoxemic Respiratory Failure
Nin-Chieh Hsu, MD, PhD; Charles Liao, MD; Chia-Hao Hsu, MD
High-Flow Nasal Oxygen vs Standard Oxygen Therapy and Length of Hospital Stay in Children With Acute Hypoxemic Respiratory Failure—Reply
Donna Franklin, BN, MBA, PhD; Franz E. Babl, MD; Andreas Schibler, MD
CORRECTION
Incorrect Data in Table
JAMA MASTHEAD
JAMA
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