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IN THIS ISSUE OF JAMA
Audio Highlights
Audio Editors' Summary: Intra-arterial Alteplase for Acute Ischemic Stroke, Long-term Outcomes of Acute Respiratory Failure in Early Childhood, Take-Home Doses of Opioid Agonist Therapy, and more
ORIGINAL INVESTIGATION
Caring for the Critically Ill Patient
Association of Acute Respiratory Failure in Early Childhood With Long-term Neurocognitive Outcomes
R. Scott Watson, MD, MPH; Sue R. Beers, PhD; Lisa A. Asaro, MS; et al.
Editorial: Long-term Neurocognitive Morbidity After a Single Episode of Respiratory Failure in Children; Steven L. Shein, MD; Alexandre T. Rotta, MD
Association Between Increased Dispensing of Opioid Agonist Therapy Take-Home Doses and Opioid Overdose and Treatment Interruption and Discontinuation
Tara Gomes, PhD; Tonya J. Campbell, MPH; Sophie A. Kitchen, MSc; et al.
PRELIMINARY COMMUNICATION
Effect of Intra-arterial Alteplase vs Placebo Following Successful Thrombectomy on Functional Outcomes in Patients With Large Vessel Occlusion Acute Ischemic Stroke: The CHOICE Randomized Clinical Trial
Arturo Renú, MD; Mónica Millán, MD; Luis San Román, MD; et al.
JAMA Medical News Audio: Highlights From the International Stroke Conference
Audio Clinical Review: Thrombolytics and Endovascular Thrombectomy for Acute Ischemic Stroke
Editorial: Intra-arterial Thrombolysis to Target Occlusions in Distal Arteries and the Microcirculation; Pooja Khatri, MD, MSc
RESEARCH LETTER
Reoperation for Recurrence Up to 10 Years After Hernia Repair
Ryan Howard, MD; Jyothi Thumma, MPH; Anne Ehlers, MD, MPH; et al.
Frequency and Risk of Emergency Medical Service Interhospital Transportation of Patients With Acute Lower Respiratory Tract Illness During the COVID-19 Pandemic in the US
Sadia H. Sarzynski, MD, MS; Alex Mancera, MSBT; Clay Mann, PhD, MS; et al.
Earn CME credit
VIEWPOINT
Time to Retire the Concept of Transient Ischemic Attack
J. Donald Easton, MD; S. Claiborne Johnston, MD, PhD
Closing Evidence Gaps in Clinical Prevention: A Report From the National Academies of Sciences, Engineering, and Medicine
Tracy A. Lieu, MD, MPH; Alexis Wojtowicz, BA; Kathleen Stratton, PhD
Vaccination for Dengue Prevention
Laura E. Adams, DVM, MPH; Steve Waterman, MD, MPH; Gabriela Paz-Bailey, MD, MSc, PhD
A PIECE OF MY MIND
The Farewell
Jay A. Pandit, MD
EDITORIAL
Intra-arterial Thrombolysis to Target Occlusions in Distal Arteries and the Microcirculation
Pooja Khatri, MD, MSc
Long-term Neurocognitive Morbidity After a Single Episode of Respiratory Failure in Children
Steven L. Shein, MD; Alexandre T. Rotta, MD
REVIEW
Diagnosis and Treatment of Pulmonary Sarcoidosis: A Review
John A. Belperio, MD; Faisal Shaikh, MD; Fereidoun G. Abtin, MD; et al.
Earn CME credit
JAMA GUIDE TO STATISTICS AND METHODS
Assessing Unexpected Circumstances That Lead to Modifications in Clinical Trial Design, Conduct, or Analysis: Application of the CONSERVE Reporting Guideline
Maria Mori Brooks, PhD; Stephen R. Wisniewski, PhD
Earn CME credit
JAMA CLINICAL GUIDELINES SYNOPSIS
CDC Sexually Transmitted Infections Treatment Guidelines, 2021
Aniruddha Hazra, MD; Maggie W. Collison, MD; Andrew M. Davis, MD, MPH
Earn CME credit
MEDICAL NEWS & PERSPECTIVES
How Prolonged Isolation Affects People With Parkinson Disease During the COVID-19 Pandemic
Melissa Suran, PhD, MSJ
JAMA Medical News Audio: February 2022 Medical News Summary
NEWS FROM THE JAMA NETWORK
Erenumab Safe, Effective for Patients With Migraine With Aura
Anita Slomski
Screening in Early Intervention Increases Autism Diagnoses
Anita Slomski
Metabolic Surgery Associated With Less Severe COVID-19
Anita Slomski
Global Cancer Burden Grew From 2010 to 2019
Anita Slomski
NEWS FROM THE FOOD AND DRUG ADMINISTRATION
Injectable siRNA Approved for Lowering Cholesterol
Howard D. Larkin
Therapy Approved for All Types of Severe Asthma
Howard D. Larkin
Draft Guidance on Remote Data Acquisition in Trials
Howard D. Larkin
POETRY AND MEDICINE
More
Wynne Morrison, MD, MBE
JAMA REVISITED
Current Comment
The Work of the Scientist
JAMA PATIENT PAGE
What Is Acute Ischemic Stroke?
Kristin Walter, MD, MS
AUDIO
Audio Editors' Summary
Intra-arterial Alteplase for Acute Ischemic Stroke, Long-term Outcomes of Acute Respiratory Failure in Early Childhood, Take-Home Doses of Opioid Agonist Therapy, and more
JAMA Medical News Audio
Highlights From the International Stroke Conference
JAMA Medical News Audio
February 2022 Medical News Summary
Audio Clinical Review
Thrombolytics and Endovascular Thrombectomy for Acute Ischemic Stroke
COMMENT & RESPONSE
Amenorrhea Evaluation and Management
Yue Zhang, BS; Yizhou Huang, MD; Jianhong Zhou, MD, PhD
Amenorrhea Evaluation and Management—Reply
Sarah Pitts, MD; Amy D. DiVasta, MD, MMSc; Catherine M. Gordon, MD, MSc
Review of Cardiogenic Shock After Acute Myocardial Infarction
Jonathan R. Dalzell, MBChB, MD
Review of Cardiogenic Shock After Acute Myocardial Infarction—Reply
Marc D. Samsky, MD; Sunil V. Rao, MD
Discussion of Diagnostic Excellence
Michael D. Lockshin, MD
Discussion of Diagnostic Excellence—Reply
Daniel Yang, MD; Harvey V. Fineberg, MD, PhD; Karen Cosby, MD
CORRECTION
Incorrect Author Name
Incorrect Definition
JAMA MASTHEAD
JAMA
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