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New Issue: Cerebral Venous Sinus Thrombosis Following Ad26.COV2.S Vaccination, Triple vs Dual Inhaler Therapy for Asthma, Transcatheter Treatment of Cardiac Valvular Disease, and more

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New Issue

JUNE 22/29, 2021; VOLUME 325, NUMBER 24,
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IN THIS ISSUE OF JAMA

Audio Highlights

Audio Editors' Summary: Cerebral Venous Sinus Thrombosis Following Ad26.COV2.S Vaccination, Triple vs Dual Inhaler Therapy for Asthma, Transcatheter Treatment of Cardiac Valvular Disease, and more

ORIGINAL INVESTIGATION

US Case Reports of Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Ad26.COV2.S Vaccination, March 2 to April 21, 2021

Isaac See, MD; John R. Su, MD, PhD, MPH; Allison Lale, MD, MPH; et al.

Editorial: Assessing a Rare and Serious Adverse Event Following Administration of the Ad26.COV2.S Vaccine; Ruth A. Karron, MD; Nigel S. Key, MD; Joshua M. Sharfstein, MD

Association Between Vaccination With BNT162b2 and Incidence of Symptomatic and Asymptomatic SARS-CoV-2 Infections Among Health Care Workers

Yoel Angel, MD, MBA; Avishay Spitzer, MD; Oryan Henig, MD; et al.

Earn CME credit

Triple vs Dual Inhaler Therapy and Asthma Outcomes in Moderate to Severe Asthma: A Systematic Review and Meta-analysis

Lisa H. Y. Kim, MD; Carol Saleh, MD; Anna Whalen-Browne, MD; et al.

Earn CME credit

RESEARCH LETTER

Asymptomatic and Symptomatic SARS-CoV-2 Infections After BNT162b2 Vaccination in a Routinely Screened Workforce

Li Tang, PhD; Diego R. Hijano, MD, MSc; Aditya H. Gaur, MD, MBBS; et al.

Earn CME credit

Association of Initial Treatment With Antibiotics vs Surgery With Treatment Success and Disability in Subgroups of Children With Uncomplicated Appendicitis

Peter C. Minneci, MD, MHSc; Erinn M. Hade, PhD; Gregory A. Metzger, MD; et al.

VIEWPOINT

When Vaccine Apathy, Not Hesitancy, Drives Vaccine Disinterest

Stacy Wood, PhD; Kevin Schulman, MD

Implementing High-Quality Primary Care: A Report From the National Academies of Sciences, Engineering, and Medicine

Robert L. Phillips Jr, MD, MSPH; Linda A. McCauley, RN, PhD; Christopher F. Koller, MA

A National Goal to Advance Health Equity Through Value-Based Payment

Joshua M. Liao, MD, MSc; Risa J. Lavizzo-Mourey, MD, MBA; Amol S. Navathe, MD, PhD

Progress With the All of Us Research Program: Opening Access for Researchers

Andrea H. Ramirez, MD, MS; Kelly A. Gebo, MD, MPH; Paul A. Harris, PhD

A PIECE OF MY MIND

Vaccinated but Not Protected—Living Immunocompromised During the Pandemic

Lindsay Ryan, MD

Earn CME credit

EDITORIAL

Assessing a Rare and Serious Adverse Event Following Administration of the Ad26.COV2.S Vaccine

Ruth A. Karron, MD; Nigel S. Key, MD; Joshua M. Sharfstein, MD

REVIEW

Transcatheter Treatment of Valvular Heart Disease: A Review

Laura J. Davidson, MD, MS; Charles J. Davidson, MD

Earn CME credit

Audio Clinical Review: Transcatheter Treatments of Valvular Heart Disease

Video: Transcatheter Aortic Valve Implantation (TAVI)

Video: Transcatheter Aortic Valve-in-Valve Procedure After Bioprosthetic Valve Failure

Video: Transcatheter Mitral Valve-in-Valve Procedure After Bioprosthetic Valve Failure

Video: Mitral Valve Transcatheter Edge-to-Edge Repair

JAMA INSIGHTS

The Pandemic Stay-at-Home Order and Opioid-Involved Overdose Fatalities

Maryann Mason, PhD; Ponni Arukumar, MD; Joe Feinglass, PhD

Earn CME credit

Clinical Update

Assessment of Depressive Symptoms in Medically Ill Patients

Patrick Baumgart, MD; Thomas Garrick, MD

MEDICAL NEWS & PERSPECTIVES

Community-Based Organizations Step Up to Confront HIV in Southern States

Bridget M. Kuehn, MSJ

JAMA Medical News Audio: June 2021 Medical News Summary

Quick Uptakes

Could Statins Do More Than Lower Cholesterol in Patients With COVID-19?

Rita Rubin, MA

Earn CME credit

NEWS FROM THE CENTERS FOR DISEASE CONTROL AND PREVENTION

Adults Lag Behind Children in Reduced Head Injuries From Biking

Bridget M. Kuehn, MSJ

Botulism Guidelines Aim to Help Prepare Clinicians for Outbreaks

Bridget M. Kuehn, MSJ

CLINICAL TRIALS UPDATE

Online Exercise Plus Text Messages Improve Knee Osteoarthritis

Anita Slomski

Vagus Nerve Stimulation Restores Arm Function Years After Stroke

Anita Slomski

Tranexamic Acid Reduces Blood Loss After Cesarean, but Not by Much

Anita Slomski

Hospital-at-Home Rivals Inpatient Care for Some Older Adults

Anita Slomski

Ready-to-Use Glucagon Analogue Quickly Reverses Hypoglycemia

Anita Slomski

HEALTH AGENCIES UPDATE

Funding for Rural COVID-19 Care

Rita Rubin, MA

Vaccination in Residential Facilities

Rita Rubin, MA

NIH Addresses COVID-19 Disparities

Rita Rubin, MA

POETRY AND MEDICINE

His Service Dog

Richard Bronson, MD

JAMA REVISITED

Book Notices

JAMA PATIENT PAGE

Artificial Heart Valves

William C. Frankel, BS; Tom C. Nguyen, MD

AUDIO

Audio Editors' Summary

Cerebral Venous Sinus Thrombosis Following Ad26.COV2.S Vaccination, Triple vs Dual Inhaler Therapy for Asthma, Transcatheter Treatment of Cardiac Valvular Disease, and more

Audio Clinical Review

Transcatheter Treatments of Valvular Heart Disease

JAMA Medical News Audio

June 2021 Medical News Summary

VIDEO

Transcatheter Aortic Valve Implantation (TAVI)

Transcatheter Aortic Valve-in-Valve Procedure After Bioprosthetic Valve Failure

Transcatheter Mitral Valve-in-Valve Procedure After Bioprosthetic Valve Failure

Mitral Valve Transcatheter Edge-to-Edge Repair

COMMENT & RESPONSE

Review of Hip and Knee Osteoarthritis

Raymond E. Phillips, MD

Review of Hip and Knee Osteoarthritis—Reply

Jeffrey N. Katz, MD, MSc; Kaetlyn Arant, BA; Richard F. Loeser, MD

Effect of Restrictive or Liberal Blood Transfusion on Major Cardiovascular Events in Patients With Acute Myocardial Infarction and Anemia

Tomohiko Sato, MD, PhD; Rui Terada, MD, PhD; Toshiyuki Ikeda, MD

Effect of Restrictive or Liberal Blood Transfusion on Major Cardiovascular Events in Patients With Acute Myocardial Infarction and Anemia—Reply

Gregory Ducrocq, MD, PhD; Tabassome Simon, MD, PhD; P. Gabriel Steg, MD; et al.

CORRECTION

Addition of Nonauthor Collaborator Names of the INTUBE Study Collaborators

JAMA MASTHEAD

JAMA

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