IN THIS ISSUE OF JAMA
Audio Highlights
Audio Editors' Summary: Cerebral Venous Sinus Thrombosis Following Ad26.COV2.S Vaccination, Triple vs Dual Inhaler Therapy for Asthma, Transcatheter Treatment of Cardiac Valvular Disease, and more
ORIGINAL INVESTIGATION
US Case Reports of Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Ad26.COV2.S Vaccination, March 2 to April 21, 2021
Isaac See, MD; John R. Su, MD, PhD, MPH; Allison Lale, MD, MPH; et al.
Editorial: Assessing a Rare and Serious Adverse Event Following Administration of the Ad26.COV2.S Vaccine; Ruth A. Karron, MD; Nigel S. Key, MD; Joshua M. Sharfstein, MD
Association Between Vaccination With BNT162b2 and Incidence of Symptomatic and Asymptomatic SARS-CoV-2 Infections Among Health Care Workers
Yoel Angel, MD, MBA; Avishay Spitzer, MD; Oryan Henig, MD; et al.
Earn CME credit
Triple vs Dual Inhaler Therapy and Asthma Outcomes in Moderate to Severe Asthma: A Systematic Review and Meta-analysis
Lisa H. Y. Kim, MD; Carol Saleh, MD; Anna Whalen-Browne, MD; et al.
Earn CME credit
RESEARCH LETTER
Asymptomatic and Symptomatic SARS-CoV-2 Infections After BNT162b2 Vaccination in a Routinely Screened Workforce
Li Tang, PhD; Diego R. Hijano, MD, MSc; Aditya H. Gaur, MD, MBBS; et al.
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Association of Initial Treatment With Antibiotics vs Surgery With Treatment Success and Disability in Subgroups of Children With Uncomplicated Appendicitis
Peter C. Minneci, MD, MHSc; Erinn M. Hade, PhD; Gregory A. Metzger, MD; et al.
VIEWPOINT
When Vaccine Apathy, Not Hesitancy, Drives Vaccine Disinterest
Stacy Wood, PhD; Kevin Schulman, MD
Implementing High-Quality Primary Care: A Report From the National Academies of Sciences, Engineering, and Medicine
Robert L. Phillips Jr, MD, MSPH; Linda A. McCauley, RN, PhD; Christopher F. Koller, MA
A National Goal to Advance Health Equity Through Value-Based Payment
Joshua M. Liao, MD, MSc; Risa J. Lavizzo-Mourey, MD, MBA; Amol S. Navathe, MD, PhD
Progress With the All of Us Research Program: Opening Access for Researchers
Andrea H. Ramirez, MD, MS; Kelly A. Gebo, MD, MPH; Paul A. Harris, PhD
A PIECE OF MY MIND
Vaccinated but Not Protected—Living Immunocompromised During the Pandemic
Lindsay Ryan, MD
Earn CME credit
EDITORIAL
Assessing a Rare and Serious Adverse Event Following Administration of the Ad26.COV2.S Vaccine
Ruth A. Karron, MD; Nigel S. Key, MD; Joshua M. Sharfstein, MD
REVIEW
Transcatheter Treatment of Valvular Heart Disease: A Review
Laura J. Davidson, MD, MS; Charles J. Davidson, MD
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Audio Clinical Review: Transcatheter Treatments of Valvular Heart Disease
Video: Transcatheter Aortic Valve Implantation (TAVI)
Video: Transcatheter Aortic Valve-in-Valve Procedure After Bioprosthetic Valve Failure
Video: Transcatheter Mitral Valve-in-Valve Procedure After Bioprosthetic Valve Failure
Video: Mitral Valve Transcatheter Edge-to-Edge Repair
JAMA INSIGHTS
The Pandemic Stay-at-Home Order and Opioid-Involved Overdose Fatalities
Maryann Mason, PhD; Ponni Arukumar, MD; Joe Feinglass, PhD
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Clinical Update
Assessment of Depressive Symptoms in Medically Ill Patients
Patrick Baumgart, MD; Thomas Garrick, MD
MEDICAL NEWS & PERSPECTIVES
Community-Based Organizations Step Up to Confront HIV in Southern States
Bridget M. Kuehn, MSJ
JAMA Medical News Audio: June 2021 Medical News Summary
Quick Uptakes
Could Statins Do More Than Lower Cholesterol in Patients With COVID-19?
Rita Rubin, MA
Earn CME credit
NEWS FROM THE CENTERS FOR DISEASE CONTROL AND PREVENTION
Adults Lag Behind Children in Reduced Head Injuries From Biking
Bridget M. Kuehn, MSJ
Botulism Guidelines Aim to Help Prepare Clinicians for Outbreaks
Bridget M. Kuehn, MSJ
CLINICAL TRIALS UPDATE
Online Exercise Plus Text Messages Improve Knee Osteoarthritis
Anita Slomski
Vagus Nerve Stimulation Restores Arm Function Years After Stroke
Anita Slomski
Tranexamic Acid Reduces Blood Loss After Cesarean, but Not by Much
Anita Slomski
Hospital-at-Home Rivals Inpatient Care for Some Older Adults
Anita Slomski
Ready-to-Use Glucagon Analogue Quickly Reverses Hypoglycemia
Anita Slomski
HEALTH AGENCIES UPDATE
Funding for Rural COVID-19 Care
Rita Rubin, MA
Vaccination in Residential Facilities
Rita Rubin, MA
NIH Addresses COVID-19 Disparities
Rita Rubin, MA
POETRY AND MEDICINE
His Service Dog
Richard Bronson, MD
JAMA REVISITED
Book Notices
JAMA PATIENT PAGE
Artificial Heart Valves
William C. Frankel, BS; Tom C. Nguyen, MD
AUDIO
Audio Editors' Summary
Cerebral Venous Sinus Thrombosis Following Ad26.COV2.S Vaccination, Triple vs Dual Inhaler Therapy for Asthma, Transcatheter Treatment of Cardiac Valvular Disease, and more
Audio Clinical Review
Transcatheter Treatments of Valvular Heart Disease
JAMA Medical News Audio
June 2021 Medical News Summary
VIDEO
Transcatheter Aortic Valve Implantation (TAVI)
Transcatheter Aortic Valve-in-Valve Procedure After Bioprosthetic Valve Failure
Transcatheter Mitral Valve-in-Valve Procedure After Bioprosthetic Valve Failure
Mitral Valve Transcatheter Edge-to-Edge Repair
COMMENT & RESPONSE
Review of Hip and Knee Osteoarthritis
Raymond E. Phillips, MD
Review of Hip and Knee Osteoarthritis—Reply
Jeffrey N. Katz, MD, MSc; Kaetlyn Arant, BA; Richard F. Loeser, MD
Effect of Restrictive or Liberal Blood Transfusion on Major Cardiovascular Events in Patients With Acute Myocardial Infarction and Anemia
Tomohiko Sato, MD, PhD; Rui Terada, MD, PhD; Toshiyuki Ikeda, MD
Effect of Restrictive or Liberal Blood Transfusion on Major Cardiovascular Events in Patients With Acute Myocardial Infarction and Anemia—Reply
Gregory Ducrocq, MD, PhD; Tabassome Simon, MD, PhD; P. Gabriel Steg, MD; et al.
CORRECTION
Addition of Nonauthor Collaborator Names of the INTUBE Study Collaborators
JAMA MASTHEAD
JAMA
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