New Issue: Dexamethasone Dose in Adults With Severe COVID-19, Mental Stress-Induced Myocardial Ischemia and Cardiovascular Events, Medicare Outcomes From the Oncology Care Model, and more

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New Issue

NOVEMBER 9, 2021; VOLUME 326, NUMBER 18
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IN THIS ISSUE OF JAMA

Audio Highlights

Audio Editors' Summary: Dexamethasone Dose in Adults With Severe COVID-19, Mental Stress-Induced Myocardial Ischemia and Cardiovascular Events, Medicare Outcomes From the Oncology Care Model, and more

ORIGINAL INVESTIGATION

Caring for the Critically Ill Patient

Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia: The COVID STEROID 2 Randomized Trial

The COVID STEROID 2 Trial Group

Editorial: Glucocorticoid Dose in COVID-19: Lessons for Clinical Trials During a Pandemic; Steven A. Webb, MD, PhD; Alisa M. Higgins, PhD; Colin J. McArthur, MBChB

Video: Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia

Association of Mental Stress–Induced Myocardial Ischemia With Cardiovascular Events in Patients With Coronary Heart Disease

Viola Vaccarino, MD, PhD; Zakaria Almuwaqqat, MD; Jeong Hwan Kim, MD; et al.

Earn CME credit

Editorial: Mental Stress–Induced Myocardial Ischemia: When the Mind Controls the Fate of the Heart; Paco E. Bravo, MD; Thomas P. Cappola, MD, ScM

Association of Participation in the Oncology Care Model With Medicare Payments, Utilization, Care Delivery, and Quality Outcomes

Nancy L. Keating, MD, MPH; Shalini Jhatakia, MA; Gabriel A. Brooks, MD, MPH; et al.

Earn CME credit

Editorial: Medicare Spending, Utilization, and Quality in the Oncology Care Model; Raymond U. Osarogiagbon, MBBS; Samyukta Mullangi, MD; Deborah Schrag, MD, MPH

RESEARCH LETTER

Characteristics and Outcomes of Products Seeking Competitive Generic Therapy Designation and Exclusivity

Harinder Singh Chahal, PharmD, MSc; Annabelle C. Fowler, PhD; Rinku Patel, PharmD; et al.

COVID-19 Incidence and Mortality in Federal and State Prisons Compared With the US Population, April 5, 2020, to April 3, 2021

Neal Marquez, MPH; Julie A. Ward, MN, RN; Kalind Parish, MA; et al.

Medical Specialty Board Parental, Caregiver, and Medical Leave Policy Updates After 2021 American Board of Medical Specialties Mandate

Kirti Magudia, MD, PhD; Shauna R. Campbell, DO; Erika L. Rangel, MD, MS; et al.

VIEWPOINT

A Policy Prescription for Reducing Health Disparities—Achieving Pharmacoequity

Utibe R. Essien, MD, MPH; Stacie B. Dusetzina, PhD; Walid F. Gellad, MD, MPH

Audio Author Interview: A Continued Focus on Equity Through Pharmacoequity and Digital Health Equity: Two Current Viewpoints

Focusing on Digital Health Equity

Courtney R. Lyles, PhD; Robert M. Wachter, MD; Urmimala Sarkar, MD, MPH

Audio Author Interview: A Continued Focus on Equity Through Pharmacoequity and Digital Health Equity: Two Current Viewpoints

The Affordable Care Act Resurrected: Curtailing the Ranks of the Uninsured

Eli Y. Adashi, MD, MS; Daniel P. O’Mahony, MSLS; I. Glenn Cohen, JD

A PIECE OF MY MIND

Little Acts and Big Differences: Perspectives on Civility in Medicine

Danielle Dougherty, MD; Erin E. Perrone, MD

EDITORIAL

Glucocorticoid Dose in COVID-19: Lessons for Clinical Trials During a Pandemic

Steven A. Webb, MD, PhD; Alisa M. Higgins, PhD; Colin J. McArthur, MBChB

Video: Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia

Mental Stress–Induced Myocardial Ischemia: When the Mind Controls the Fate of the Heart

Paco E. Bravo, MD; Thomas P. Cappola, MD, ScM

Medicare Spending, Utilization, and Quality in the Oncology Care Model

Raymond U. Osarogiagbon, MBBS; Samyukta Mullangi, MD; Deborah Schrag, MD, MPH

REVIEW

Cardiogenic Shock After Acute Myocardial Infarction: A Review

Marc D. Samsky, MD; David A. Morrow, MD, MPH; Alastair G. Proudfoot, MBChB, PhD; et al.

Earn CME credit

JAMA CLINICAL CHALLENGE

Blue Pigmentation of the Skin, Sclera, and Teeth

Nina A. Ran, MD; Matthew L. Hedberg, MD, PhD; Misha Rosenbach, MD

Earn CME credit

FROM THE MEDICAL LETTER ON DRUGS AND THERAPEUTICS

Higher-Dose Naloxone Nasal Spray (Kloxxado) for Opioid Overdose

MEDICAL NEWS & PERSPECTIVES

The Flawed Science of Antibody Testing for SARS-CoV-2 Immunity

Jennifer Abbasi

Quick Uptakes

Survey Describes How Patients With Arthritis Get Moving

Rebecca Voelker, MSJ

NEWS FROM THE CENTERS FOR DISEASE CONTROL AND PREVENTION

Targeted Efforts Needed to Curb Arthritis-Related Disability

Bridget M. Kuehn, MSJ

Low PrEP Awareness, Referrals for Black, Hispanic, and Latino People

Bridget M. Kuehn, MSJ

BIOTECH INNOVATIONS

Pfizer Launches Phase 1 mRNA Flu Vaccine Trial

Jennifer Abbasi

Flu Vaccine Candidate Elicits Enhanced Immune Response

Jennifer Abbasi

“Polymutant” Spike Points Way Toward More Durable COVID-19 Vaccine

Jennifer Abbasi

Closed Loop Device May Alleviate Treatment-Resistant Depression

Jennifer Abbasi

Guided Ultrasound Opens Blood-Brain Barrier to Cancer Drugs

Jennifer Abbasi

Augmented Cane Could Help People With Visual Impairments

Jennifer Abbasi

THE ARTS AND MEDICINE

Gustav Klimt’s The Kiss—Art and the Biology of Early Human Development

Dai Hyun Kim, MD, PhD; Hyunmi Park, MBChB, PhD, Med Ed; Im Joo Rhyu, MD, PhD

POETRY AND MEDICINE

Poem by a Woman With Glaucoma

Terri Kirby Erickson, BA

JAMA REVISITED

Routine Smallpox Vaccination

JAMA PATIENT PAGE

Separation Anxiety Disorder

Avani K. Patel, MD, MHA; Beverly Bryant, MD

AUDIO

Audio Editors' Summary

Dexamethasone Dose in Adults With Severe COVID-19, Mental Stress-Induced Myocardial Ischemia and Cardiovascular Events, Medicare Outcomes From the Oncology Care Model, and more

Audio Author Interview

A Continued Focus on Equity Through Pharmacoequity and Digital Health Equity: Two Current Viewpoints

VIDEO

 

Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia

COMMENT & RESPONSE

Iatrogenic Delivery for Suspected Fetal Growth Restriction and Childhood School Outcomes

Gordon C. S. Smith, MD, PhD, DSc

Iatrogenic Delivery for Suspected Fetal Growth Restriction and Childhood School Outcomes

Niel F. Miele, MD

Iatrogenic Delivery for Suspected Fetal Growth Restriction and Childhood School Outcomes—Reply

Roshan John Selvaratnam, BMedSc(Hons); Euan Morrison Wallace, MD; Mary-Ann Davey, DPH

The Effect of Cytisine vs Varenicline on Smoking Cessation

Adam Edward Lang, PharmD

The Effect of Cytisine vs Varenicline on Smoking Cessation—Reply

Ryan J. Courtney, PhD; Piotr Tutka, MD; Michael Farrell, PhD

Medical Debt in the US From 2009 to 2020

Nishant Uppal, BS; Carrie Lubitz, MD, MPH; Benjamin James, MD, MS

Medical Debt in the US From 2009 to 2020—Reply

Neale Mahoney, PhD; Francis Wong, PhD; Wesley Yin, PhD

CORRECTION

Addition of Nonauthor Collaborator Names of the COMEBAC Study

Incorrect Patient Data Reported

JAMA MASTHEAD

JAMA

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