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IN THIS ISSUE OF JAMA
Audio Highlights
Audio Editors' Summary: Casirivimab and Imdevimab for Early Asymptomatic SARS-CoV-2 Infection, Hypothermia vs Normothermia for Cardiogenic Shock and Extracorporeal Membrane Oxygenation, Familial Idiopathic Dilated Cardiomyopathy, and more
ORIGINAL INVESTIGATION
Effect of Subcutaneous Casirivimab and Imdevimab Antibody Combination vs Placebo on Development of Symptomatic COVID-19 in Early Asymptomatic SARS-CoV-2 Infection: A Randomized Clinical Trial
Meagan P. O’Brien, MD; Eduardo Forleo-Neto, MD; Neena Sarkar, PhD; et al.
Earn CME credit
Editorial: Realizing the Potential of Anti–SARS-CoV-2 Monoclonal Antibodies for COVID-19 Management; Jonathan Z. Li, MD; Rajesh T. Gandhi, MD
Caring for the Critically Ill Patient
Effect of Moderate Hypothermia vs Normothermia on 30-Day Mortality in Patients With Cardiogenic Shock Receiving Venoarterial Extracorporeal Membrane Oxygenation: A Randomized Clinical Trial
Bruno Levy, MD, PhD; Nicolas Girerd, MD, PhD; Julien Amour, MD, PhD; et al.
Earn CME credit
Prevalence and Cumulative Risk of Familial Idiopathic Dilated Cardiomyopathy
Gordon S. Huggins, MD; Daniel D. Kinnamon, PhD; Garrie J. Haas, MD; et al.
Earn CME credit
Editorial: Identifying Dilated Cardiomyopathy Through Family-Based Screening; Krishna G. Aragam, MD, MS
RESEARCH LETTER
Trends in Use of Melatonin Supplements Among US Adults, 1999-2018
Jingen Li, MD, PhD; Virend K. Somers, MD, PhD; Hao Xu, MD, PhD; et al.
False-Positive Results in Rapid Antigen Tests for SARS-CoV-2
Joshua S. Gans, PhD; Avi Goldfarb, PhD; Ajay K. Agrawal, PhD; et al.
Earn CME credit
VIEWPOINT
Improving Traumatic Brain Injury Care and Research: A Report From the National Academies of Sciences, Engineering, and Medicine
Katherine Bowman, PhD; Chanel Matney, PhD; Donald M. Berwick, MD, MPP
Mitigating the Long-term Health Risks of Adverse Pregnancy Outcomes
Lynn M. Yee, MD, MPH; Eliza C. Miller, MD, MS; Philip Greenland, MD
Hierarchical Payment Models—A Path for Coordinating Population- and Episode-Based Payment Models
William H. Shrank, MD, MSHS; Michael E. Chernew, PhD; Amol S. Navathe, MD, PhD
A PIECE OF MY MIND
The Language of Failure
Iris T. Lee, MD
EDITORIAL
Realizing the Potential of Anti–SARS-CoV-2 Monoclonal Antibodies for COVID-19 Management
Jonathan Z. Li, MD; Rajesh T. Gandhi, MD
Earn CME credit
Identifying Dilated Cardiomyopathy Through Family-Based Screening
Krishna G. Aragam, MD, MS
REVIEW
Diagnosis and Management of Multiple Myeloma: A Review
Andrew J. Cowan, MD; Damian J. Green, MD; Mary Kwok, MD; et al.
Earn CME credit
Audio Clinical Review: Diagnosis and Management of Multiple Myeloma
JAMA INSIGHTS
Clinical Update
Dry Eye Disease: An Update in 2022
Farida E. Hakim, MD; Asim V. Farooq, MD
Earn CME credit
JAMA DIAGNOSTIC TEST INTERPRETATION
Diffusing Capacity of the Lungs for Carbon Monoxide Test
Neil MacIntyre, MD; Aparna Balasubramanian, MD; David Kaminsky, MD
Earn CME credit
MEDICAL NEWS & PERSPECTIVES
Preparing Hospitals’ Medical Oxygen Delivery Systems for a Respiratory “Twindemic”
Melissa Suran, PhD, MSJ
JAMA Medical News Audio: January 2022 Medical News Summary
Quick Uptakes
Study: Business Booms for Unlicensed and Unproven Stem Cell Treatments
Rita Rubin, MA
NEWS FROM THE JAMA NETWORK
Female Patients Fare Worse With Male Surgeons
Anita Slomski
Cataract Surgery May Stave Off Dementia Among Older Patients
Anita Slomski
Strokes Occur Later and Are Less Severe Than 2 Decades Ago
Anita Slomski
New Data on Retinopathy in Youth-Onset Type 2 Diabetes
Anita Slomski
NEWS FROM THE FOOD AND DRUG ADMINISTRATION
First Modified-Risk Combusted Cigarettes Are Authorized
Rebecca Voelker, MSJ
Drug Approved to Prevent Graft-vs-Host Disease
Rebecca Voelker, MSJ
A New Option Is Approved for Patients With Myasthenia Gravis
Rebecca Voelker, MSJ
POETRY AND MEDICINE
Fasciculation
Samuel J. Belfer, MD, PhD
JAMA REVISITED
The Adaptation of Infant Welfare Work to Private Practice
JAMA PATIENT PAGE
What Is Multiple Myeloma?
Juliet Silberstein, MD, MPH; Sascha Tuchman, MD, MHS; Shakira J. Grant, MBBS
Audio Clinical Review: Diagnosis and Management of Multiple Myeloma
AUDIO
Audio Editors' Summary
Casirivimab and Imdevimab for Early Asymptomatic SARS-CoV-2 Infection, Hypothermia vs Normothermia for Cardiogenic Shock and Extracorporeal Membrane Oxygenation, Familial Idiopathic Dilated Cardiomyopathy, and more
Audio Clinical Review
Diagnosis and Management of Multiple Myeloma
JAMA Medical News Audio
January 2022 Medical News Summary
COMMENT & RESPONSE
Vasopressin and Methylprednisolone vs Placebo and Return of Spontaneous Circulation in Patients With In-Hospital Cardiac Arrest
Julien Cobert, MD; Allyson Chapman, MD; Alexander Smith, MD, MS, MPH
Vasopressin and Methylprednisolone vs Placebo and Return of Spontaneous Circulation in Patients With In-Hospital Cardiac Arrest
Sunn Hoah Kelvin Yap, BSc
Vasopressin and Methylprednisolone vs Placebo and Return of Spontaneous Circulation in Patients With In-Hospital Cardiac Arrest
Richard Jiménez-Cuja, MD; Victor Salazar-Orihuela, MD; Luis Llanco-Albornoz, PhD
Vasopressin and Methylprednisolone vs Placebo and Return of Spontaneous Circulation in Patients With In-Hospital Cardiac Arrest—Reply
Lars W. Andersen, MD, MPH, PhD, DMSc; Asger Granfeldt, MD, PhD, DMSc
Association of Tramadol vs Codeine Prescription Dispensation With Mortality and Other Adverse Outcomes
Chao-Hsien Chen, MD; Cheng-Yi Wang, MD; Chih-Cheng Lai, MD
Association of Tramadol vs Codeine Prescription Dispensation With Mortality and Other Adverse Outcomes
Shu Hsin Yi, MB; Yung-Heng Lee, MD, PhD; James Wei, MD, PhD
Association of Tramadol vs Codeine Prescriptions With Mortality and Other Adverse Clinical Outcomes—Reply
Junqing Xie, BSMed, MSc; Carlen Reyes, MD, PhD; Daniel Prieto-Alhambra, MD, PhD
JAMA MASTHEAD
JAMA
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