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This Week in JAMA
Audio Highlights
Zilebesiran for Uncontrolled Hypertension, Platelet Transfusion Guidelines, Uveitis Review and more
Original Investigation
Extended Caffeine for Apnea in Moderately Preterm Infants: The MoCHA Randomized Clinical Trial
Waldemar A. Carlo, MD; Eric C. Eichenwald, MD; Benjamin A. Carper, MS; et al.
Editorial: Will Preterm Infants Come Home Sooner With Prolonged Caffeine Therapy for Apnea?; Barbara Schmidt, MD, MSc
A Multidimensional Diagnostic Approach for Chronic Obstructive Pulmonary Disease
COPDGene 2025 Diagnosis Working Group and CanCOLD Investigators
Editorial: Beyond Obstruction—A Milestone in COPD Diagnosis; Francesca Polverino, MD, PhD
Modeling Reemergence of Vaccine-Eliminated Infectious Diseases Under Declining Vaccination in the US
Mathew V. Kiang, ScD; Kate M. Bubar, PhD; Yvonne Maldonado, MD; et al.
Research Letter
Trade Tariffs on Canadian Pharmaceuticals—Implications for US Drug Supply and Costs
Mina Tadrous, PharmD, PhD; Shanzeh Chaudhry, MSc; Jan Panhuysen, MA; et al.
Uptake of and Disparities in Semaglutide and Tirzepatide Prescribing for Obesity in the US
Chungsoo Kim, PharmD, PhD; Joseph S. Ross, MD, MHS; Ania M. Jastreboff, MD, PhD; et al.
Viewpoint
The FDA’s Crisis Is Everyone’s Crisis
Patricia J. Zettler, JD; Nathan G. Cortez, JD
The Role of Affirming Language
William E. Rosa, PhD, MBE, APRN; N. F. N. Scout, PhD; Jona Tanguay, MMSc; et al.
Health and Human Services Restructuring—Threats to the US Preventive Services Task Force and Health
Alex H. Krist, MD, MPH; Scott M. Strayer, MD, MPH; Lei Charlton, MD; et al.
Preserving Research Ethics Oversight Amid Decimation of the Research Enterprise
Holly Fernandez Lynch, JD, MBE; Ivy Tillman, EdD, CIP; Elyse I. Summers, JD; et al.
Psychiatry and the Make America Healthy Again Commission
Dost Öngür, MD, PhD
A Piece of My Mind
On Healing as Restoration
Gaveen Godage, MS
Editorial
Will Preterm Infants Come Home Sooner With Prolonged Caffeine Therapy for Apnea?
Barbara Schmidt, MD, MSc
Beyond Obstruction—A Milestone in COPD Diagnosis
Francesca Polverino, MD, PhD
Review
Translational Science
The Microbiome and Cancer: A Translational Science Review
Estefania Fernandez, MD, PhD; Jennifer A. Wargo, MD, MMSc; Beth A. Helmink, MD, PhD
Earn CME credit
Audio: Microbiome and Risk for Cancer Outcomes
JAMA Insights
Communicating Medicine
Strategies for Communicating With Parents About Vaccines
Sean T. O’Leary, MD, MPH
Earn CME credit
Audio: Strategies for Talking With Parents About Vaccines
JAMA Clinical Challenge
A Woman With Facial, Neck, and Chest Swelling During Dental Cleaning
Ali Bilal Ulas, MD; Yener Aydin, MD; Mehmet Zubeyr Egilmez, MD
Earn CME credit
Editor's Note
“Man, I’d Die for a Cigarette”: When Empathy, and Healing, Are Elusive
Rafael Campo, MD, MA
Medical News
IV Fluid Shortages Persist Months After Hurricane Helene Hit a Supplier—Hospitals Have Had to Adapt
Eli Cahan, MD, MSc
Audio: May 2025 Medical News Summary
The Hidden Health Costs Associated With Legalized Sports Gambling
Kate Schweitzer
Medical News in Brief
Cancer Deaths Decline, Driven by Drop in Smoking-Related Cancers
Samantha Anderer
Semaglutide Improves Severe Liver Disease in Phase 3 Trial
Samantha Anderer
China Faces Growing Neurological Burden as Population Ages
Samantha Anderer
WHO Warns of Preventable Disease Outbreaks Amid Immunization Disruptions
Samantha Anderer
Thyroid Disease May Be Overdiagnosed, Study Finds
Samantha Anderer
Despite Prior Findings, Nicotine Pouch Use Appears to Rise in Teens
Samantha Anderer
Poetry and Medicine
20 Marlboro Reds
Scott C. Biggerstaff, DO
Editor's Note: “Man, I’d Die for a Cigarette”: When Empathy, and Healing, Are Elusive; Rafael Campo, MD, MA
JAMA Revisited
The Ideal Physician
JAMA Patient Page
What Is Chronic Migraine?
Rebecca Voelker, MSJ
Audio
Zilebesiran for Uncontrolled Hypertension, Platelet Transfusion Guidelines, Uveitis Review and more
Microbiome and Risk for Cancer Outcomes
Strategies for Talking With Parents About Vaccines
May 2025 Medical News Summary
Comment & Response
Transcriptomic Profiles in Nasal Epithelium in Youth With Asthma
Chung-Pei Ma, PhD; Chung-Chih Liao, MD, PhD; Ching-Mao Chang, MD, PhD
Transcriptomic Profiles in Nasal Epithelium in Youth With Asthma—Reply
Molin Yue, MS; Kristina Gaietto, MD, MPH; Juan C. Celedón, MD, DrPH
Pediatric Gender Medicine
Carl Streed Jr, MD, MPH; Kellan E. Baker, PhD, MPH, MA
Pediatric Gender Medicine—Reply
Moti Gorin, PhD, MBE; Jilles Smids, PhD; John Lantos, MD
AI in Medicine
Master of Digital Health Degree
Peter J. Embí, MD, MS; Genevieve B. Melton, MD, PhD; Philip R. O. Payne, PhD
AI in Medicine
Master of Digital Health Degree—Reply
Josip Car, MD, PhD; Eric J. Topol, MD
JAMA Masthead
JAMA
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