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JAMA+ Women’s Health: September 22, 2026

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Advancing clinical excellence across women's health

Expertly curated research and insights from JAMA and the JAMA Network

This week's JAMA+ Women's Health features four Original Investigations. In JAMA, a randomized trial found that intrauterine mepivacaine reduced pain during IUD placement, while another study linked adoption of adjunctive azithromycin for unscheduled cesarean delivery with fewer postpartum infections. JAMA Internal Medicine research examined menopausal hormone therapy and cardiovascular risk in midlife women with vasomotor symptoms, and a JAMA Network Open meta-analysis linked intimate partner violence against women with greater mortality among children younger than 5 years. Also included are an audio episode on AI-enabled drug safety in pregnancy and a featured video examining the association between GLP-1 receptor agonist use and reduced risk of several cancers among adults with obesity.

Explore the latest curated research, commentary, and multimedia from JAMA+ Women's Health in the featured articles below.

Original Investigation

JAMA

Intrauterine Mepivacaine Instillation vs Placebo for Pain During IUD Placement

Karin Elgemark, MD; Niklas Envall, RNM, PhD; Helena Kopp Kallner, MD, PhD

JAMA

Adoption of Adjunctive Azithromycin for Unscheduled Cesarean Delivery and Postpartum Infections

Taylor S. Freret, MD, EdM; Ethan Litman; Timothy Wen; et al

JAMA Internal Medicine

Menopausal Hormone Therapy and Cardiovascular Risk in Midlife Women With Vasomotor Symptoms

Ziyuan Wang; Sonja A. Swanson; Maria M. Brooks; et al

JAMA Network Open

Intimate Partner Violence Against Women and Mortality Among Children Younger Than 5 Years

Bereket Kefale; Aditi Roy; Daniel Gashaneh Belay; et al

Audio

AI Drug Safety in Pregnancy

FEATURED VIDEO

GLP-1 Receptor Agonists and Cancer Risk in Adults With Obesity

Linda Brubaker, MD, MS
JAMA+ Women's Health Editor in Chief

JAMA+ Women's Health features expertly curated research and insights published across the JAMA Network. Please submit your manuscripts directly to JAMA and the JAMA Network journals. More information and complete instructions are available at the For Authors page.