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JAMA Internal Medicine Online First JUNE 02, 2025

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Online First

JUNE 02, 2025
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Viewpoint

Health Care Policy and Law

Betel Nut Policy Considerations for the US

Nathaniel Wu, BS; Thomas J. Roberts, MD, MBA; Kekoa Taparra, MD, PhD, MPH; et al.

Inside Story

AI and Clinical Care

The Persons Behind Our Patients—Individualized Assessment Tools for Personalized Care

Ruchi Bhatia, MD

Original Investigation

Low-Dose Methotrexate for the Treatment of Inflammatory Knee Osteoarthritis: A Randomized Clinical Trial

Zhaohua Zhu, PhD; Qinghong Yu, MD; Xiaomei Leng, MD; et al.

Effectiveness of Text-Only E-Cigarette Warnings: A Meta-Analysis

Youjin Jang, PhD; Jessica Shaw, MA; Olivia A. Wackowski, PhD; et al.

Invited Commentary

The Future of Pharmaceuticals for Knee Osteoarthritis Needs to Move Past Methotrexate

Nancy E. Lane, MD

The Future of e-Cigarette Health Warnings

Ebbie Kalan, PhD; Olatokunbo Osibogun, PhD; Ziyad Ben Taleb, MD, PhD

Editor's Note

Ensuring Older Adults Using Cannabis Are Not Left High and Dry

Nathan M. Stall, MD, PhD; Lona Mody, MD, MSc; Kenneth E. Covinsky, MD, MPH

Research Letter

Trends in Past-Month Cannabis Use Among Older Adults

Benjamin H. Han, MD; Kevin H. Yang, MD; Charles M. Cleland, PhD; et al.

Editor's Note: Ensuring Older Adults Using Cannabis Are Not Left High and Dry; Nathan M. Stall, MD, PhD; Lona Mody, MD, MSc; Kenneth E. Covinsky, MD, MPH

Challenges in Clinical Electrocardiography

Atrioventricular Block With Abnormal P Wave

Jun-Peng Liu, PhD, MD; Jie-Fu Yang, PhD, MD; Tong Zou, PhD, MD

Earn CME credit

FROM JAMA THIS WEEK

Screening Colonoscopy Yields Among Adults Aged 45 to 49 Years After Lowering the Colon Cancer Screening Age

Jeffrey K. Lee, MD, MPH; Christopher D. Jensen, PhD, MPH; Jeffrey Hendel, MD; et al

Clinical Validation of a Circulating Tumor DNA–Based Blood Test to Screen for Colorectal Cancer

Aasma Shaukat, MD, MPH; Carol A. Burke, MD; Andrew T. Chan, MD, MPH; et al

Comment & Response

Correction Rate Matters in Severe Hyponatremia

Harish Seethapathy, MD; Aneesh B. Singhal, MD; Sagar U. Nigwekar, MD, MMSc

Correction Rate Matters in Severe Hyponatremia

Zhenjiao Liang, MD; Yingdi Yuan, MS; Xiaoping Wang, MD

Correction Rate Matters in Severe Hyponatremia

Saeed Rashaad Mohammed, BMedSci, MBBS; Surujpal Teelucksingh, MBBS, MBA, PhD

Correction Rate Matters in Severe Hyponatremia—Reply

Juan Carlos Ayus, MD; Michael L. Moritz, MD; Agustín Ciapponi, MD, MSc, PhD

Enticing but Confounded Evidence for Fast Sodium Correction

Eric Raphael Gottlieb, MD, MS; Leo Anthony Celi, MD, MPH

Enticing but Confounded Evidence for Fast Sodium Correction—Reply

Juan Carlos Ayus, MD; Michael L. Moritz, MD; Agustín Ciapponi, MD, MSc, PhD

TRENDING NOW ON JAMA Internal Medicine

Glucose-Lowering Medications, Glycemia, and Cognitive Outcomes: The GRADE Randomized Clinical Trial

Trends and Disparities in Maternal Self-Reported Mental and Physical Health

Optimizing Safety for Patients Transferred From Intensive Care Units to General Medical Wards: A SIMPLER Approach

Tiotropium Initiation and Dementia Risk in Chronic Obstructive Pulmonary Disease


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