JAMA + AI Weekly Update May 24, 2025

Editor’s Picks in this week’s JAMA+ AI:

• The integration of AI in neurology promises advances in diagnosis and treatment, but the rapid development of general AI raises serious risks, including misalignment with human values and potential existential threats. Read this Viewpoint in JAMA Neurology.
• A multimodal machine learning model for delirium risk stratification was linked with improved delirium detection rates and reduced benzodiazepine and olanzapine usage in hospitalized older adults, found this quality improvement study published in JAMA Network Open.
• A prediction model based on EHR data from emergency department visits accurately identified risk factors for agitation, according to this study published in JAMA Network Open, suggesting that clinical application of the model may enhance patient-centered care.