New Issue: Transcatheter Aortic Valve Implantation vs Surgical Replacement, Oral Methylprednisolone for IgA Nephropathy, Tracheostomy in Severe Stroke, and more

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New Issue

MAY 17, 2022; VOLUME 327, NUMBER 19,
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IN THIS ISSUE OF JAMA

Audio Highlights

Audio Editors' Summary: Transcatheter Aortic Valve Implantation vs Surgical Replacement, Oral Methylprednisolone for IgA Nephropathy, Tracheostomy in Severe Stroke, and more

ORIGINAL INVESTIGATION

Effect of Transcatheter Aortic Valve Implantation vs Surgical Aortic Valve Replacement on All-Cause Mortality in Patients With Aortic Stenosis: A Randomized Clinical Trial

The UK TAVI Trial Investigators

Editorial: Treatment of Aortic Stenosis With Transcatheter Aortic Valve Implantation; Catherine M. Otto, MD, PhD; Jae-Kwan Song, MD

Video Editor's Note: Effect of Transcatheter Aortic Valve Implantation vs Surgical Aortic Valve Replacement on All-Cause Mortality in Patients With Aortic Stenosis

Effect of Oral Methylprednisolone on Decline in Kidney Function or Kidney Failure in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial

Jicheng Lv, MD; Muh Geot Wong, PhD; Michelle A. Hladunewich, MD; et al.

Editorial: Oral Glucocorticoids for IgA Nephropathy; Kirk N. Campbell, MD

Effect of Early vs Standard Approach to Tracheostomy on Functional Outcome at 6 Months Among Patients With Severe Stroke Receiving Mechanical Ventilation: The SETPOINT2 Randomized Clinical Trial

Julian Bösel, MD; Wolf-Dirk Niesen, MD; Farid Salih, MD; et al.

RESEARCH LETTER

Association Between SARS-CoV-2 Viral Load in Wastewater and Reported Cases, Hospitalizations, and Vaccinations in Milan, March 2020 to November 2021

Giovanni Nattino, PhD; Sara Castiglioni, PhD; Danilo Cereda, MD, PhD; et al.

Prediabetes and Diabetes Screening Eligibility and Detection in US Adults After Changes to US Preventive Services Task Force and American Diabetes Association Recommendations

Michael Fang, PhD, MHS; Dan Wang, MS; Justin B. Echouffo-Tcheugui, MD, PhD; et al.

SPECIAL COMMUNICATION

Ethical Considerations for the Inclusion of Patient-Reported Outcomes in Clinical Research: The PRO Ethics Guidelines

Samantha Cruz Rivera, PhD; Olalekan Lee Aiyegbusi, PhD; Jonathan Ives, PhD; et al.

Earn CME credit

Audio Clinical Review: Patient-Reported Outcomes in Clinical Trials

VIEWPOINT

The Imperative for Diversity and Inclusion in Clinical Trials and Health Research Participation

Kirsten Bibbins-Domingo, PhD, MD, MAS; Alex Helman, PhD; Victor J. Dzau, MD

COVID-19 Vaccination—Becoming Part of the New Normal

Peter Marks, MD, PhD; Janet Woodcock, MD; Robert Califf, MD

Getting Serious About Producing Health: The Ten Teams Challenge

Donald M. Berwick, MD, MPP

Firearm Homicide and Suicide During the COVID-19 Pandemic: Implications for Clinicians and Health Care Systems

Debra E. Houry, MD, MPH; Thomas R. Simon, PhD; Alexander E. Crosby, MD, MPH

A PIECE OF MY MIND

The Pandemic Determinants of Health

Jennifer Shiroky-Kochavi, MD, MPH

EDITORIAL

Treatment of Aortic Stenosis With Transcatheter Aortic Valve Implantation

Catherine M. Otto, MD, PhD; Jae-Kwan Song, MD

Oral Glucocorticoids for IgA Nephropathy

Kirk N. Campbell, MD

JAMA CLINICAL CHALLENGE

Ulcerated Plaques on the Scalp and Dorsal Hands of an Older Man

Amrita Goyal, MD; Daniel O’Leary, MD; Misha Rosenbach, MD

Earn CME credit

MEDICAL NEWS & PERSPECTIVES

The COVID-19 Pandemic Rages on for People Who Are Immunocompromised

Rita Rubin, MA

Resolving Payment Issues Is Essential to Realize Telehealth’s Promise

Howard D. Larkin

NEWS FROM THE FOOD AND DRUG ADMINISTRATION

First Breathalyzer Test to Diagnose COVID-19

Rita Rubin, MA

More Diversity in Clinical Trials

Rita Rubin, MA

Websites Selling Controlled Drugs Without a Prescription

Rita Rubin, MA

GLOBAL HEALTH

WHO Program May Eliminate Active Trachoma’s Blindness Risk by 2030

Howard D. Larkin

One-third of English GPs Plan to Quit Within 5 Years

Howard D. Larkin

Ukraine War Could Push an Additional 47 Million Into Acute Hunger

Howard D. Larkin

THE ARTS AND MEDICINE

Asclepius Revisited—Ancient Myth and 21st-Century Psychedelic Medicine

Richard R. Szuster, MD

POETRY AND MEDICINE

Scenes From the Children’s Hospital

Jeffrey G. Howard, PhD

JAMA REVISITED

Clinical Notes, Suggestions, and New Instruments: A Bedside Telephone

JAMA PATIENT PAGE

Psoriasis

Kristin Walter, MD, MS

AUDIO

Audio Editors' Summary

Transcatheter Aortic Valve Implantation vs Surgical Replacement, Oral Methylprednisolone for IgA Nephropathy, Tracheostomy in Severe Stroke, and more

Audio Clinical Review

Patient-Reported Outcomes in Clinical Trials

VIDEO

Video Editor's Note: Effect of Transcatheter Aortic Valve Implantation vs Surgical Aortic Valve Replacement on All-Cause Mortality in Patients With Aortic Stenosis

COMMENT & RESPONSE

Rapid Antigen Tests for SARS-CoV-2

Matheus Filgueira Bezerra, PhD

Rapid Antigen Tests for SARS-CoV-2—Reply

Joshua S. Gans, PhD; Avi Goldfarb, PhD; Laura Rosella, PhD

Penetrance of Deleterious Clinical Variants

Lisa Bastarache, MS; Josh F. Peterson, MD, MPH

Penetrance of Deleterious Clinical Variants—Reply

Iain S. Forrest, BS; Girish N. Nadkarni, MD; Ron Do, PhD

Moderate Hypothermia vs Normothermia and 30-Day Mortality in Patients With Cardiogenic Shock Receiving Venoarterial ECMO

Federico Pappalardo, MD; Andrea Montisci, MD

Moderate Hypothermia vs Normothermia and 30-Day Mortality in Patients With Cardiogenic Shock Receiving Venoarterial ECMO

Tatsuki Uemura, MD

Moderate Hypothermia vs Normothermia and 30-Day Mortality in Patients With Cardiogenic Shock Receiving Venoarterial ECMO—Reply

Bruno Levy, MD, PhD; Alain Combes, MD, PhD; Nicolas Girerd, MD, PhD

CORRECTION

Incorrect y-Axis and Panel Labels in Figure

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