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IN THIS ISSUE OF JAMA
Audio Highlights
Audio: Rapid-Onset Opioid vs Neuromuscular Blocker for Rapid Sequence Intubation, 180-Day Outcomes in COVID-19 in REMAP-CAP, Recommendations for Antiretrovirals for Treatment and Prevention of HIV, and more
ORIGINAL INVESTIGATION
Effect of Remifentanil vs Neuromuscular Blockers During Rapid Sequence Intubation on Successful Intubation Without Major Complications Among Patients at Risk of Aspiration: A Randomized Clinical Trial
Nicolas Grillot, MD; Gilles Lebuffe, MD, PhD; Olivier Huet, MD, PhD; et al.
Caring for the Critically Ill Patient
Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial
Writing Committee for the REMAP-CAP Investigators
Editorial: Long-term Follow-up After Critical COVID-19: REMAP-CAP Revisited; Michael L. Barnett, MD, MS; Paul E. Sax, MD
Association of Race and Ethnicity With Initial Prescription of Antiretroviral Therapy Among People With HIV in the US
Lauren C. Zalla, PhD; Stephen R. Cole, PhD; Joseph J. Eron, MD; et al.
RESEARCH LETTER
Manufacturer Revenue on Inhalers After Expiration of Primary Patents, 2000-2021
William B. Feldman, MD, DPhil, MPH; S. Sean Tu, JD, PhD; Rasha Alhiary, PharmD; et al.
Estimated Medicare Part B Savings From Inflationary Rebates
Alexander C. Egilman, BA; Aaron S. Kesselheim, MD, JD, MPH; Benjamin N. Rome, MD, MPH
COVID-19 and Excess All-Cause Mortality in the US and 20 Comparison Countries, June 2021-March 2022
Alyssa Bilinski, PhD; Kathryn Thompson, MHA; Ezekiel Emanuel, MD, PhD
SPECIAL COMMUNICATION
Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults: 2022 Recommendations of the International Antiviral Society–USA Panel
Rajesh T. Gandhi, MD; Roger Bedimo, MD; Jennifer F. Hoy, MBBS; et al.
Earn CME credit
Audio: Advances in Treatment and Prevention of HIV
VIEWPOINT
Medicaid, the Supreme Court, and Safe Care for Nursing Home Residents
Nicole Huberfeld, JD
Urgent Need for Next-Generation COVID-19 Vaccines
Peter W. Marks, MD, PhD; Philip A. Gruppuso, MD; Eli Y. Adashi, MD, MS
Audio: Urgent Need for Next-Generation COVID-19 Vaccines
A PIECE OF MY MIND
The Scent of Hope
Brooke Redmond, MD
EDITORIAL
Public Access to Scientific Research Findings and Principles of Biomedical Research—A New Policy for the JAMA Network
Kirsten Bibbins-Domingo, PhD, MD, MAS; Brian Shields, MBA; John Z. Ayanian, MD, MPP; et al.
Long-term Follow-up After Critical COVID-19: REMAP-CAP Revisited
Michael L. Barnett, MD, MS; Paul E. Sax, MD
JAMA INSIGHTS
Genomics and Precision Health
RNA Sequencing as a Diagnostic Tool
Shamika Ketkar, PhD; Lindsay C. Burrage, MD, PhD; Brendan Lee, MD, PhD
Earn CME credit
MEDICAL NEWS & PERSPECTIVES
Cardiovascular Corner—Researchers Probe Factors That May Contribute to Cardiovascular Health Disparities
Melissa Suran, PhD, MSJ
Amid Ohio Measles Outbreak, New Global Report Warns of Decreased Vaccination During COVID-19 Pandemic
Jennifer Abbasi
Audio: December 2022 Medical News Summary
NEWS FROM THE JAMA NETWORK
Mindfulness Noninferior to Medication for Quelling Anxiety
Anita Slomski
Low-Dose Aspirin Does Not Appear to Reduce Fractures
Anita Slomski
Vitamin C Improved Respiratory Health Among Children Born to Pregnant People Who Smoked
Anita Slomski
Entirely Remote Intervention Decreased BP and LDL-C in Diverse Patient Groups
Anita Slomski
NEWS FROM THE FOOD AND DRUG ADMINISTRATION
First FDA-Approved Gene Therapy for Hemophilia
Howard Larkin
New Drug Delays Type 1 Diabetes Onset
Howard Larkin
Combined COVID-19 and Flu Test Authorized for Point-of-Care Use
Howard Larkin
POETRY AND MEDICINE
Maine Medical Center
David Ebenbach, PhD
JAMA REVISITED
Present Status of “Insulin”
JAMA PATIENT PAGE
What Is Pulmonary Embolism?
Kristin Walter, MD, MS
AUDIO
Editor’s Summary Audio
Rapid-Onset Opioid vs Neuromuscular Blocker for Rapid Sequence Intubation, 180-Day Outcomes in COVID-19 in REMAP-CAP, Recommendations for Antiretrovirals for Treatment and Prevention of HIV, and more
Clinical Reviews Audio
Advances in Treatment and Prevention of HIV
Audio Author Interview
Urgent Need for Next-Generation COVID-19 Vaccines
Medical News Audio
December 2022 Medical News Summary
COMMENT & RESPONSE
Opportunities for Clinicians and Health Systems to Address Disparities in US Drug Overdose Deaths by Race and Ethnicity
Margaret Kirkegaard, MD, MPH; Bren Manaugh, LCSW-S
Opportunities for Clinicians and Health Systems to Address Disparities in US Drug Overdose Deaths by Race and Ethnicity—Reply
Mbabazi Kariisa, PhD, MPH; Puja Seth, PhD; Christopher M. Jones, PharmD, DrPH
Gout Flare and Cardiovascular Events
Ana Catarina Fonseca, MD, PhD, MPH
Gout Flare and Cardiovascular Events—Reply
Edoardo Cipolletta, MD; Laila J. Tata, PhD; Abhishek Abhishek, PhD
High- vs Low-Dose Tranexamic Acid Infusion and Need for Red Blood Cell Transfusion and Adverse Events in Cardiac Surgery
Andreas Koster, MD, PhD; Nikolai Hulde, MD; Armin Zittermann, PhD
High- vs Low-Dose Tranexamic Acid Infusion and Need for Red Blood Cell Transfusion and Adverse Events in Cardiac Surgery—Reply
Jia Shi, MD; Chenghui Zhou, MD; Zhe Zheng, MD
JAMA MASTHEAD
JAMA
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